Granulomatosis linfomatoide cerebral primaria en paciente VIH positivo: Caso clinico

Schalper, Kurt A.; Valbuena, José R.

doi:10.4067/s0034-98872011000200012

Rev. méd. Chile

2011

DOI: 10.4067/s0034-98872011000200012

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Granulomatosis linfomatoide cerebral primaria en paciente VIH positivo: Caso clinico

Kurt A. Schalper

José R. Valbuena

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Cited by 6 publications

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“…In the case of brain involvement, reactive astrogliosis can occur in response to tissue injury (ie, inflammation) in LYG lesions. 12,13 Considering these established findings, infiltration of inflammatory cells including EBV-positive atypical B cells and reactive astrogliosis probably occurred in and around the Gd-enhanced lesions in the present case. Therefore, uptake of 11 C-methionine and 18 F-FDG could reflect the degree of inflammatory cell infiltration in lesions.…”

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confidence: 51%

Brain PET Imaging of 11C-Methionine, 18F-FDG, and 18F-THK5351 in a Case of Lymphomatoid Granulomatosis

et al. 2022

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A 52-year-old woman complained of upper respiratory symptoms and subsequently developed Wallenberg syndrome. Chest CT and brain MRI revealed multiple nodular lesions in the lungs and brain. She was pathologically diagnosed with low-grade lymphomatoid granulomatosis by lung biopsy. Brain PET examinations using 11 C-methionine, 18 F-FDG, and 18 F-THK5351 were performed. Uptake of 11 C-methionine and 18 F-FDG was slightly increased in some lesions, likely reflecting the degree of inflammatory cell infiltration. 18 F-THK5351 uptake was significantly increased in all lesions, likely reflecting the degree of reactive astrogliosis. This case illustrates the utility of PET studies for diagnosing lymphomatoid granulomatosis and provides insight into its pathophysiology.

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confidence: 51%

Brain PET Imaging of 11C-Methionine, 18F-FDG, and 18F-THK5351 in a Case of Lymphomatoid Granulomatosis

et al. 2022

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Cutaneous human immunodeficiency virus (HIV)‐associated lymphomatoid granulomatosis: complete regression following antiretroviral therapy

et al. 2017

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Isolated lymphomatoid granulomatosis of the central nervous system: A case report and literature review

Zhang

et al. 2019

Neuropathology

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Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive lymphoproliferative disease which can involve multiple organs of the body and is most common in the lungs. Its pathological features are proliferation of large atypical B‐cells related to Epstein–Barr virus, T‐cell infiltration and tissue necrosis. This disease is rare, and LYG which uniquely involves the central nervous system (CNS) is extremely rare. In this paper, we report a case of isolated lymphomatoid granulomatosis of the CNS (iCNS‐LYG) diagnosed by histological biopsy and we review the clinical features of all similar cases reported in the past 46 years. A total of 49 cases of iCNS‐LYG have been reported to date. The clinical, imaging and pathological features of iCNS‐LYG are discussed in combination with a literature review.

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Granulomatosis linfomatoide cerebral primaria en paciente VIH positivo: Caso clinico

Cited by 6 publications

References 22 publications

Brain PET Imaging of 11C-Methionine, 18F-FDG, and 18F-THK5351 in a Case of Lymphomatoid Granulomatosis

Brain PET Imaging of 11C-Methionine, 18F-FDG, and 18F-THK5351 in a Case of Lymphomatoid Granulomatosis

Cutaneous human immunodeficiency virus (HIV)‐associated lymphomatoid granulomatosis: complete regression following antiretroviral therapy

Isolated lymphomatoid granulomatosis of the central nervous system: A case report and literature review

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