Granuloma Annulare in Identical Twins

Localized granuloma annulare associated with autoimmune thyroid disease in a patient with a positive family history for autoimmune polyglandular syndrome type II

“…However, the origin is most likely immunologic (1). In at least some cases there is a mechanism of inheritance (2,3). Interestingly, there is also evidence linking granuloma annulare and autoimmune thyroiditis/insulin-dependent diabetes mellitus (IDDM) that comes from both limited epidemiologic data (4,5) and clinical observations (1,6,7).…”