Granulocytic Sarcoma Presenting as a Solitary Nodule of Skin in a Patient with Waldenstromʼs Macroglobulinemia

Choi, Hongyung; Orentreich, David S.; Kornblee, Leonard; Muhlfelder, Thomas W.

doi:10.1097/00000372-198902000-00008

Cited by 7 publications

(2 citation statements)

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“…The development of acute myeloid leukemia in Waldenström's macroglobulinemia is very rare. A literature search revealed 16 such cases, including Majumdar's case [1] and other 13 cases his group reviewed [2][3][4][5][6][7][8][9][10]. There was another case of acute myeloblastic leukemia and macroglobulinemia reported by Tangun et al in 1968 in Turkish [11], which was not included in Majumbar's review [1], and whether any alkylating agent was administered prior to the development of acute myeloblastic leukemia is unknown.…”

Section: Discussionmentioning

confidence: 99%

“…The concurrence of acute myeloid leukemia is very rare in cases of previously untreated Waldenström's macroglobulinemia. In 1993, Majumdar and Slater reported a case of Waldenström's macroglobulinemia terminating in acute myeloid leukemia [1], and reviewed 13 similar cases [2][3][4][5][6][7][8][9][10] as well, although they did not include another case reported by Tangun et al in 1968 [11]. Among those 15 cases, there were only two patients who had not received chemotherapy prior to the development of acute myeloid leukemia.…”

Section: Introductionmentioning

confidence: 99%

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Occurrence of acute monocytic leukemia in a case of untreated Waldenström's macroglobulinemia

2002

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Occurrence of acute monocytic leukemia in a case of untreated Waldenström's macroglobulinemia

2002

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Multiple Papules and Plaques in a Patient With Ovarian Carcinoma

Fridus

Rodman²,

Cyran³

et al. 1993

Arch Dermatol

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Primary aleukemic myeloid leukemia cutis treated successfully with combination chemotherapy: report of a case and review of the literature

Chang

Shih

Kuo

2003

Annals of Hematology

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Aleukemic myeloid leukemia cutis is extremely rare and is usually associated with early marrow relapse and poor treatment outcome. We report a 39-year-old man presenting with generalized cutaneous nodules. The initial diagnosis was cutaneous malignant lymphoma. New skin lesions and a nasopharyngeal mass developed during phototherapy. Biopsy of the cutaneous and nasopharyngeal lesions revealed monotonous blast cell infiltration. Cytochemical stain and immunophenotypic analysis of the fresh cell suspension made from another skin biopsy specimen identified that the neoplastic cells belonged to the monocytic lineage. A diagnosis of primary aleukemic leukemia cutis was established. The leukemic cells expressed CD56 but did not carry AML-1/ETO, CBFbeta/MYH11, or common MLL fusion transcripts. He received standard induction therapy for acute myeloid leukemia, followed by high-dose postremission chemotherapy and has been disease-free for more than 30 months. To the best of our knowledge, the current case has the longest disease-free survival among those reported.

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Granulocytic Sarcoma Presenting as a Solitary Nodule of Skin in a Patient with Waldenstromʼs Macroglobulinemia

Cited by 7 publications

References 1 publication

Occurrence of acute monocytic leukemia in a case of untreated Waldenström's macroglobulinemia

Occurrence of acute monocytic leukemia in a case of untreated Waldenström's macroglobulinemia

Multiple Papules and Plaques in a Patient With Ovarian Carcinoma

Primary aleukemic myeloid leukemia cutis treated successfully with combination chemotherapy: report of a case and review of the literature

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