Granulocytic sarcoma (chloroma) of the Gingiva: Report of a case

A fatal case of rapid gingival enlargement: Case report with brief review

“…However, this lesion should always be suspected in individuals affected by myeloproliferative neoplasms. [ 8 9 20 21 ] In the present case, the peripheral smear was normal despite histological and immunohistochemical confirmation as MS.…”

“…[ 6 7 8 ] However, a concise IHC panel including CD20, CD43, CD68 and MPO can successfully identify the majority of extramedullary myeloid tumors. [ 8 9 20 21 ] In the present case, H and E-stained sections showed hyperplastic epithelium [ Figure 4 ] with sheets of tumor cells in the underlying connective tissue [ Figure 5 ]. The findings of H and E were not conclusive, as these features might be seen in any of the lymphocytic lesions discussed above.…”

“…Earlier studies have shown that MS was commonly reported in patients with chronic myeloid leukemia in blast crisis. [ 9 20 21 ] However, the current review had shown more number of acute myeloid leukemia transforming into MS.…”

A fatal case of rapid gingival enlargement: Case report with brief review

“…However, this lesion should always be suspected in individuals affected by myeloproliferative neoplasms. [ 8 9 20 21 ] In the present case, the peripheral smear was normal despite histological and immunohistochemical confirmation as MS.…”

“…[ 6 7 8 ] However, a concise IHC panel including CD20, CD43, CD68 and MPO can successfully identify the majority of extramedullary myeloid tumors. [ 8 9 20 21 ] In the present case, H and E-stained sections showed hyperplastic epithelium [ Figure 4 ] with sheets of tumor cells in the underlying connective tissue [ Figure 5 ]. The findings of H and E were not conclusive, as these features might be seen in any of the lymphocytic lesions discussed above.…”

“…Earlier studies have shown that MS was commonly reported in patients with chronic myeloid leukemia in blast crisis. [ 9 20 21 ] However, the current review had shown more number of acute myeloid leukemia transforming into MS.…”

Myeloid Sarcoma Occurring Concurrently With Drug‐Induced Gingival Enlargement

“…A gingivectomy was performed, but due to recurrent swelling, an incisional biopsy was done 1 year later. The biopsy confirmed MS. A report by Eisenberg et al 16 described a 33‐year‐old male presenting with multiple erythematous granular nodules on the right maxillary and mandibular molar areas. The patient was biopsied and the lesion was diagnosed as MS.…”

Intraoral Myeloid sarcoma with bilateral involvement: Case report

“…The occurrence of intraoral MS as multiple masses involving multiple sites is extremely rare, with only 2 reported cases in the literature 3,8 . Intraoral MS usually occurs concomitantly with or subsequent to the development of AML; it is most seen in patients with the subtype AML-M1 (myeloblastic leukaemia without maturation) or AML-M2 (myeloblastic leukaemia with maturation) 5 , whereas rarely, it precedes the appearance of AML as in our case.…”

A fatal case of rapid gingival enlargement: Case report with brief review

“…However, this lesion should always be suspected in individuals affected by myeloproliferative neoplasms. [ 8 9 20 21 ] In the present case, the peripheral smear was normal despite histological and immunohistochemical confirmation as MS.…”

“…[ 6 7 8 ] However, a concise IHC panel including CD20, CD43, CD68 and MPO can successfully identify the majority of extramedullary myeloid tumors. [ 8 9 20 21 ] In the present case, H and E-stained sections showed hyperplastic epithelium [ Figure 4 ] with sheets of tumor cells in the underlying connective tissue [ Figure 5 ]. The findings of H and E were not conclusive, as these features might be seen in any of the lymphocytic lesions discussed above.…”

“…Earlier studies have shown that MS was commonly reported in patients with chronic myeloid leukemia in blast crisis. [ 9 20 21 ] However, the current review had shown more number of acute myeloid leukemia transforming into MS.…”

Myeloid Sarcoma Occurring Concurrently With Drug‐Induced Gingival Enlargement

“…A gingivectomy was performed, but due to recurrent swelling, an incisional biopsy was done 1 year later. The biopsy confirmed MS. A report by Eisenberg et al 16 described a 33‐year‐old male presenting with multiple erythematous granular nodules on the right maxillary and mandibular molar areas. The patient was biopsied and the lesion was diagnosed as MS.…”

Intraoral Myeloid sarcoma with bilateral involvement: Case report

“…The occurrence of intraoral MS as multiple masses involving multiple sites is extremely rare, with only 2 reported cases in the literature 3,8 . Intraoral MS usually occurs concomitantly with or subsequent to the development of AML; it is most seen in patients with the subtype AML-M1 (myeloblastic leukaemia without maturation) or AML-M2 (myeloblastic leukaemia with maturation) 5 , whereas rarely, it precedes the appearance of AML as in our case.…”

A fatal case of rapid gingival enlargement: Case report with brief review

“…However, this lesion should always be suspected in individuals affected by myeloproliferative neoplasms. [ 8 9 20 21 ] In the present case, the peripheral smear was normal despite histological and immunohistochemical confirmation as MS.…”

“…[ 6 7 8 ] However, a concise IHC panel including CD20, CD43, CD68 and MPO can successfully identify the majority of extramedullary myeloid tumors. [ 8 9 20 21 ] In the present case, H and E-stained sections showed hyperplastic epithelium [ Figure 4 ] with sheets of tumor cells in the underlying connective tissue [ Figure 5 ]. The findings of H and E were not conclusive, as these features might be seen in any of the lymphocytic lesions discussed above.…”

“…Earlier studies have shown that MS was commonly reported in patients with chronic myeloid leukemia in blast crisis. [ 9 20 21 ] However, the current review had shown more number of acute myeloid leukemia transforming into MS.…”

Myeloid Sarcoma Occurring Concurrently With Drug‐Induced Gingival Enlargement

“…A gingivectomy was performed, but due to recurrent swelling, an incisional biopsy was done 1 year later. The biopsy confirmed MS. A report by Eisenberg et al 16 described a 33‐year‐old male presenting with multiple erythematous granular nodules on the right maxillary and mandibular molar areas. The patient was biopsied and the lesion was diagnosed as MS.…”

Intraoral Myeloid sarcoma with bilateral involvement: Case report

“…The occurrence of intraoral MS as multiple masses involving multiple sites is extremely rare, with only 2 reported cases in the literature 3,8 . Intraoral MS usually occurs concomitantly with or subsequent to the development of AML; it is most seen in patients with the subtype AML-M1 (myeloblastic leukaemia without maturation) or AML-M2 (myeloblastic leukaemia with maturation) 5 , whereas rarely, it precedes the appearance of AML as in our case.…”