1974
DOI: 10.1056/nejm197402142900703
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Graft-versus-Host Disease after Intrauterine and Exchange Transfusions for Hemolytic Disease of the Newborn

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Cited by 202 publications
(45 citation statements)
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“…For example, utilization of chromosome polymorphisms to establish the parental origin of chromosomes [e.g., in bone marrow transplantation (38), gene mapping (39), or prenatal diagnosis (40)] should be greatly facilitated. Also, an increase in the sensitivity with which more subtle polymorphisms can be detected might expand the scope of chromosomal polymorphisms as a tool in studying population cytogenetics and evolution.…”
Section: Discussionmentioning
confidence: 99%
“…For example, utilization of chromosome polymorphisms to establish the parental origin of chromosomes [e.g., in bone marrow transplantation (38), gene mapping (39), or prenatal diagnosis (40)] should be greatly facilitated. Also, an increase in the sensitivity with which more subtle polymorphisms can be detected might expand the scope of chromosomal polymorphisms as a tool in studying population cytogenetics and evolution.…”
Section: Discussionmentioning
confidence: 99%
“…Several observations lend support to this hypothesis. For instance, graft vs. host disease has been observed after intrauterine and exchange transfusions (17,19). Furthermore, skin homograft rejection is delayed in the normal newborn (7) and Uhr et al (25) have shown diminished rate and degree of skin sensitization to dinitrochlorobenzene in neonates.…”
Section: Speculationmentioning
confidence: 99%
“…However, exchange transfusion requires massive fresh blood and is associated with such complications as anti-blood cell antibody production, infection and graftversus-host disease (Operz et al 1973 ;Parkman et al 1974). In an effort to increase the effectiveness of exchange transfusion and eliminate its shortcomings, we developed an on-line P.E.…”
Section: Discussionmentioning
confidence: 99%