Graft Rejection and Graft Failure After Anterior Lamellar Versus Penetrating Keratoplasty

Bilateral Microkeratome-Assisted Anterior Lamellar Contralateral Corneal Autograft

“…1,4 This procedure avoids the unnecessary replacement of an otherwise healthy endothelial layer and reduces the increased risk of rejection while achieving visual outcomes similar to those of PK. 1,3,5 Although immune-mediated rejection is less likely with ALK when compared with PK, there is still some risk with any allograft transplantation. 5 The use of a corneal autograft eliminates the possibility of rejection.…”

“…1,3,5 Although immune-mediated rejection is less likely with ALK when compared with PK, there is still some risk with any allograft transplantation. 5 The use of a corneal autograft eliminates the possibility of rejection. Unilateral rotating penetrating corneal autografts and contralateral penetrating corneal autografts are well-described.…”

Visual outcome in patients undergoing penetrating keratoplasty

“…Now a days due to better instrumentation trend is shifting towards lamellar keratoplasty because of less incidence of graft rejection and better visual outcome. 5 Present study on visual outcome after penetrating keratoplasty consisted of 30 postoperative cases from eye department of G.G.S. medical college, Faridkot.…”

Donor Tissue Selection for Anterior Lamellar Keratoplasty

“…Preserving the recipient corneal endothelium results in a lower rejection incidence, an absence of endothelial rejection, a lower endothelial cell loss after transplantation, and a favorable cost-effectiveness ratio. [10][11][12][13][14][15] This makes possible, at least theoretically, the use of donor tissue with poor endothelium because this layer will not be grafted. The objectives of the present study were to assess the influence of donor characteristics on the outcome of ALK and to evaluate whether corneal donor tissue considered unsuitable for penetrating or posterior lamellar keratoplasty due to poor endothelial condition may be safely used for ALK.…”