volume 320, issue 3, PG304-G318 2021
DOI: 10.1152/ajpgi.00275.2020
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Abstract: Non-alcoholic Fatty Liver Disease (NAFLD), characterized by the abnormal deposition of lipids within the liver not due to alcohol consumption, is a growing epidemic affecting over 30% of the US population. Both simple fatty liver and its more severe counterpart, nonalcoholic steatohepatitis (NASH) represent one of the most common forms of liver disease. Recently, several G protein-coupled receptors (GPCRs) have emerged as targets for therapeutic intervention for these disorders. These include those with known…

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