Gonococcal endocarditis: A case series demonstrating modern presentation of an old disease

Tricuspid valve gonococcal endocarditis: fourth case report

“…The aortic valve is involved in 50% of cases, followed by the mitral valve in 30% of cases. 6 Historically diagnosing GE has been challenging, because Neisseria is difficult to grow even with appropriate culture media. On average, more than six blood cultures are required.…”

“…[1][2][3][4] The number of reported cases has decreased with the advent of antibiotics. 1,5,6 There are only two case reports of tricuspid valve involvement occurring in the postantibiotic era. 2,3 In both reports, the patients were young and had a past history of gonococcal infection.…”

Kulturnegative Endokarditis: Ätiologie, Diagnostik, Management und Therapie

“…Die Erkrankung tritt vornehmlich bei jüngeren Patienten auf, wobei vorausgehende lokalisierte Gonokokkeninfektionen (z.B. Urethritis) nur in einer Minorität der Patienten festzustellen sind [38,39].…”

Systemic gonococcal infection.

“…Although involvement of the meninges, heart valves and bone have been reported these remain rare with 1-3% of patients with DGI progressing to endocarditis, most commonly affecting the aortic valve'4 54 55-the last reported case of gonococcal endocarditis was however over 50 years ago. In gonococcal meningitis the patient generally has features Ross typical of meningism but the other features of DGI are absent.5657…”