Gold Nanoparticle Enlargement Coupled with Fluorescence Quenching for Highly Sensitive Detection of Analytes

Lim, Seong Yoon; Kim, Jae Hong; Lee, Joon Seok; Park, Chan Beum

doi:10.1021/la903248w

Cited by 53 publications

(27 citation statements)

References 19 publications

(18 reference statements)

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“…The combination of size and shape provides very unique electronic, magnetic, catalytic, and optical properties to these metal nanoparticles that can be exploitable in the rapidly growing nanoindustries. There are exciting potential of nanoparticles in catalysis [2][3][4][5][6][7], DNA sequence recognition [8][9][10], nonlinear optical devices [11], biological sensors [12,13], information storage [14], and plasmonics [15]. These properties are mainly due to their optical and electronic attributes modulated by their shape and size [16,17].…”

Section: Introductionmentioning

confidence: 99%

Biogenic gold nanotriangles from Saccharomonospora sp., an endophytic actinomycetes of Azadirachta indica A. Juss.

et al. 2013

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Microbial biofabrication is emerging as eco-friendly, simpler, and reproducible alternative to chemical synthesis of metals and semiconductor nanoparticles, allowing generation of rare geometrical forms such as nanotriangles and nanoprisms. Highly confined nanostructures like triangles/prisms are interesting class of nanoparticles due to their unique optical properties exploitable in biomedical diagnostics and biosensors. Here, we report for the first time a single-step biological protocol for the synthesis of gold nanotriangles using extract of endophytic actinomycetes Saccharomonospora sp., isolated from surface sterilized root tissues of Azadirachta indica A. Juss., when incubated with an aqueous solution of chloroaurate ions (AuCl − 4 /1 mM). Thin, flat occasionally prismatic gold nanotriangles were produced when aqueous chloroaurate ions reacted with the cell-free extract as well as with the biomass of endophytic Saccharomonospora. It was evidenced from sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis that proteins of 42 and 50 kD were involved in biosynthesis as well as in stabilization of the nanoparticles. The particle growth process was monitored by UV-vis spectroscopy, and the morphological characterization was carried out by transmission electron microscopy and atomic force microscopy together with X-ray powder diffractions. Although the exact mechanism for this shape-oriented synthesis is not clear so far, the possibility of achieving nanoparticle shape control in a microbial system is exciting.

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Section: Introductionmentioning

confidence: 99%

Biogenic gold nanotriangles from Saccharomonospora sp., an endophytic actinomycetes of Azadirachta indica A. Juss.

et al. 2013

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“…Among various synthesis methods, plant-mediated synthesis is preferred due to its cost effectiveness and environment-friendly nature [3,4]. GNP have applications in therapeutic [5], catalysis [2], immunoassay and immunosensing [6], diagnostic and drug delivery [7][8][9][10], analyte sensing [11][12][13], cancer cell diagnostics and selective photothermal therapy [14,15], photoacoustic imaging [16,17] and cancer treatment [18]. Various plant extracts have been explored for the synthesis of GNP, namely tamarind [19], Aloe vera [20], Pelargonium graveolens [21], Diopyros kaki [22], Eucalyptus camaldulensis and Pelargonium roseum [23], coriander [24], Scutellaria barbata [25], lemongrass [26], Datura metel, Carica papaya and Solanum melongena [27].…”

Section: Introductionmentioning

confidence: 99%

Characterisation of gold nanoparticles synthesised by leaf and seed extract ofSyzygium cuminiL.

Kumar

Yadav

2012

Journal of Experimental Nanoscience

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Here, Syzygium cumini leaf extract (LE) and seed extract (SE) were explored for the synthesis of gold nanoparticles (GNP). LE and SE as well as their polar (water) fractions showed potential for GNP synthesis. Comparative synthesis kinetics and morphological characterisation studies revealed the synthesis of smaller sized GNP by LE than SE. Only polar (water) fractions showed potential for GNP synthesis, which are smaller in size compared to their respective extracts. SE contained more polyphenols and biochemical constituents than LE and therefore, showed higher synthesis rate and bigger sized GNP. Atomic force microscope and scanning electron microscope analysis indicated that both extracts and their fractions catalysed the synthesis of spherical GNP. The average size of GNP synthesised by LE, leaf water fraction (LWF), SE and seed water fraction (SWF) were 24, 23, 35 and 32 nm, respectively. Fourier transform infrared analysis identified the biomolecules involved in the synthesis and stability of GNP. This study documented the potential of S. cumini for the synthesis of GNP in addition to silver nanoparticles (SNP). However, nature and types of polyphenols involved in GNP synthesis seem to be different from that involved in SNP synthesis. This might be the possible reason for smaller sized GNP that SNP.

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“…Recently, a new mechanism with the system of Au NPs and fluorescent molecular probes 31 was developed for the detection of CWAs (Scheme 6) [31]. The absorption of Au NPs focuses at 515 to 530 nm, which depends on the size of the Au NPs.…”

Section: Methodsmentioning

confidence: 99%

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

Bai

Zhang

et al. 2010

Front. Chem. China

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Owing to their direct toxic effects on human beings, animals, and plants, chemical warfare agents (CWAs) and their mimics have become widespread in chemical warfare and agriculture. The considerable concerns about their entry into biological systems and the residues in environment stimulate the development of rapid and sensitive methods for the detection and analysis of this family of compounds. In the progress of sensitive, selective, and fast responsive detection, fluorescent molecular probes have been widely used in the detection of CWAs in recent years. Here the recent reports on the design of fluorescent molecular probes and their advantages in the detection of CWAs were reviewed. Furthermore, the extensive interests accelerate the development of novel fluorescent molecular probes and detection techniques in this field.

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Gold Nanoparticle Enlargement Coupled with Fluorescence Quenching for Highly Sensitive Detection of Analytes

Cited by 53 publications

References 19 publications

Biogenic gold nanotriangles from Saccharomonospora sp., an endophytic actinomycetes of Azadirachta indica A. Juss.

Biogenic gold nanotriangles from Saccharomonospora sp., an endophytic actinomycetes of Azadirachta indica A. Juss.

Characterisation of gold nanoparticles synthesised by leaf and seed extract ofSyzygium cuminiL.

Fluorescent molecular probes for the detection of chemical warfare agents and their mimics

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