GOLD B-C-D groups or GOLD II-III-IV grades

Moreira, Graciane Laender; Donária, Leila; Furlanetto, Karina Couto; Paes, Thaís; Sant’Anna, Thaís; Hernandes, Nídia A.; Pitta, Fábio

doi:10.1177/1479972315573528

Cited by 16 publications

(7 citation statements)

References 39 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous research reporting on PA across the different quadrants are mainly based on mMRC to classify patients and only measured PA at one time point. Moreira and colleagues did not find any difference in objectively measured activity time between quadrants B to D nor between the former stages [ 36 ], the latter is in contrast with available literature [ 10 ]. In line with our results, lower levels of PA of patients in quadrant B and D were concluded in the study of Boland,et al [ 37 ], although the methodology of PA measurement was not specified.…”

Section: Discussionmentioning

confidence: 98%

Physical Activity Characteristics across GOLD Quadrants Depend on the Questionnaire Used

et al. 2016

View full text Add to dashboard Cite

BackgroundThe GOLD multidimensional classification of COPD severity combines the exacerbation risk with the symptom experience, for which 3 different questionnaires are permitted. This study investigated differences in physical activity (PA) in the different GOLD quadrants and patient’s distribution in relation to the questionnaire used.Methods136 COPD patients (58±21% FEV1 predicted, 34F/102M) completed COPD assessment test (CAT), clinical COPD questionnaire (CCQ) and modified Medical Research Council (mMRC) questionnaire. Exacerbation history, spirometry and 6MWD were collected. PA was objectively measured for 2 periods of 1 week, 6 months apart, in 5 European centres; to minimise seasonal and clinical variation the average of these two periods was used for analysis.ResultsGOLD quadrants C+D had reduced PA compared with A+B (3824 [2976] vs. 5508 [4671] steps.d-1, p<0.0001). The choice of questionnaire yielded different patient distributions (agreement mMRC-CAT κ = 0.57; CCQ-mMRC κ = 0.71; CCQ-CAT κ = 0.72) with different clinical characteristics. PA was notably lower in patients with an mMRC score ≥2 (3430 [2537] vs. 5443 [3776] steps.d-1, p <0.001) in both the low and high risk quadrants.ConclusionsUsing different questionnaires changes the patient distribution and results in different clinical characteristics. Therefore, standardization of the questionnaire used for classification is critical to allow comparison of different studies using this as an entry criterion.Clinical Trial RegistrationClinicalTrials.gov NCT01388218

show abstract

Section: Discussionmentioning

confidence: 98%

Physical Activity Characteristics across GOLD Quadrants Depend on the Questionnaire Used

et al. 2016

View full text Add to dashboard Cite

show abstract

“…The intransitive frame may be underinformative in at least two ways. First, it is compatible with two different construals, arising from the fact that a DP denoting a plurality occupies the subject position (e.g., Scha, 1981 ; Gillon, 1987 ; Landman, 1989a , b ; Link, 1991 ; Verkuyl and van der Does, 1991 ). Under one interpretation of the conjoined subject, the collective interpretation, the property is predicated of the entire group (or sum) of participants, and there is one single, atomic event to which the verb refers, in which each member of the plurality is a participant.…”

Section: Introductionmentioning

confidence: 83%

Lexical Disambiguation in Verb Learning: Evidence from the Conjoined-Subject Intransitive Frame in English and Mandarin Chinese

2016

View full text Add to dashboard Cite

When presented with a novel verb in a transitive frame (X is Ving Y), young children typically select a causative event referent, rather than one in which agents engage in parallel, non-causative synchronous events. However, when presented with a conjoined-subject intransitive frame (X and Y are Ving), participants (even adults, as we show) are at chance. Although in some instances, children older than three can obtain above-chance-level performance, these experiments still appear to rely upon a within-experiment contrast with the transitive frame. This leads us to ask whether children can achieve success with the intransitive frame without such a contrast among constructions, and map a novel verb appearing in such a frame onto a non-causative meaning. Building on recent evidence that adverbial modifiers can support word learning for adjectives and for verbs (when both nominal and verbal candidate interpretations are considered) by directing children to a particular construal of a scene, we test the hypothesis that a semantically informative modifier, together, will provide children with additional lexical information that allows them to narrow down verb meaning and identify a non-causative interpretation for a novel verb appearing in the conjoined-subject intransitive frame. We find that for English-speaking children and adults it does, but only when together directly modifies the verb phrase, suggesting that participants appeal to compositionality and not just the brute addition of another word, even one that is semantically meaningful, to arrive at the intended interpretation. Children acquiring Mandarin Chinese, in contrast, do not succeed with the translation-equivalent of together (although adult speakers do), but they do with dōu (roughly, the distributive quantifier “each”). Our results point to a valuable source of information young children learning verbs: modifiers with familiar semantics.

show abstract

“…Although a cut-off point for the 6MWD has yet to be established in Brazil, previous studies have used a cut-off point of 80% of the predicted value. 17 , 18 A cut-off point expressed as a percentage of the predicted value might be more appropriate for two reasons: 1) it takes into account individual patient characteristics; and 2) it prevents the introduction of an absolute value bias when it is applied to different populations, the 6MWD being longer in Brazil than in other countries. 16 …”

Section: Introductionmentioning

confidence: 99%

Can the six-minute walk distance predict the occurrence of acute exacerbations of COPD in patients in Brazil?

et al. 2017

Self Cite

View full text Add to dashboard Cite

Objective:To evaluate whether a six-minute walk distance (6MWD) of < 80% of the predicted value can predict the occurrence of acute exacerbations of COPD in patients in Brazil over a 2-year period. Methods:This was a retrospective cross-sectional study involving 50 COPD patients in Brazil. At enrollment, anthropometric data were collected and patients were assessed for pulmonary function (by spirometry) and functional exercise capacity (by the 6MWD). The patients were subsequently divided into two groups: 6MWD ≤ 80% of predicted and 6MWD > 80% of predicted. The occurrence of acute exacerbations of COPD over 2 years was identified by analyzing medical records and contacting patients by telephone. Results:In the sample as a whole, there was moderate-to-severe airflow obstruction (mean FEV1 = 41 ± 12% of predicted) and the mean 6MWD was 469 ± 60 m (86 ± 10% of predicted). Over the 2-year follow-up period, 25 patients (50%) experienced acute exacerbations of COPD. The Kaplan-Meier method showed that the patients in whom the 6MWD was ≤ 80% of predicted were more likely to have exacerbations than were those in whom the 6MWD was > 80% of predicted (p = 0.01), whereas the Cox regression model showed that the former were 2.6 times as likely to have an exacerbation over a 2-year period as were the latter (p = 0.02). Conclusions:In Brazil, the 6MWD can predict acute exacerbations of COPD over a 2-year period. The risk of experiencing an acute exacerbation of COPD within 2 years is more than twice as high in patients in whom the 6MWD is ≤ 80% of predicted.

show abstract

GOLD B-C-D groups or GOLD II-III-IV grades

Cited by 16 publications

References 39 publications

Physical Activity Characteristics across GOLD Quadrants Depend on the Questionnaire Used

Physical Activity Characteristics across GOLD Quadrants Depend on the Questionnaire Used

Lexical Disambiguation in Verb Learning: Evidence from the Conjoined-Subject Intransitive Frame in English and Mandarin Chinese

Can the six-minute walk distance predict the occurrence of acute exacerbations of COPD in patients in Brazil?

Contact Info

Product

Resources

About