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Cited by 16 publications
(11 citation statements)
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“…Recently, the mechanism of CYP1B1 regulation by glutamate (Yu et al 2019) has been demonstrated. Glutamate is a primary amino acid neurotransmitter known for its role as an excitatory neurotransmitter in the mammalian nervous system.…”
Section: Regulationmentioning
confidence: 99%
“…Recently, the mechanism of CYP1B1 regulation by glutamate (Yu et al 2019) has been demonstrated. Glutamate is a primary amino acid neurotransmitter known for its role as an excitatory neurotransmitter in the mammalian nervous system.…”
Section: Regulationmentioning
confidence: 99%
“…Conversely, AA is seemingly unable to activate SOCE [24,25,26]. A recent investigation suggested that AA may be converted by cytochrome P450 2U1 epoxygenase into 20-HETE also in hCMEC/D3 cells and rat brain microvessels [27]. Furthermore, a preliminary report showed that AA may trigger intracellular Ca 2+ signals in primary human brain microvascular endothelial cells, but the underlying signalling pathway was not clearly elucidated and their ability to promote NO was not evaluated [23].…”
Section: Introductionmentioning
confidence: 99%
“…Notably, elevation of urinary 11-HETE strongly increased the odds of AMD development. Although not much is known about 11-HETE in AMD, high levels in circulation was associated with coronary syndrome [34] and lung cancer [35], and take part in neuroinflammation [36] and neurotransmission [37]. In recent report, free 11-HETE was five times higher in obese individuals who had high BMI and waist circumference [38].…”
Section: Discussionmentioning
confidence: 99%