Glomus tumour: An analysis of 43 patients and review of the literature

Heys, Steven Darryll; Brittenden, Julie; Atkinson, P L; Eremin, O.

doi:10.1002/bjs.1800790423

Cited by 102 publications

(98 citation statements)

References 12 publications

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“…Although they are well recognized as a cause of pain in the digits, glomus tumors have erroneously been believed less common in extradigital locations [17,33]. Extradigital presentations comprised up to 67% of glomus tumors in the recent literature [15,33].…”

Section: Discussion and Treatmentmentioning

confidence: 99%

“…Most patients are evaluated repeatedly and have their conditions misdiagnosed [15,19,26,28,33]. According to one report, glomus tumor was considered by the initial physician in only 19% of patients and in less than 50% upon referral to a specialist [17]. When the index of suspicion for a glomus tumor is low, the physician constructs and investigates a list of differential diagnoses that is based on the anatomic site, rather than the nature of the complaint.…”

Section: Discussion and Treatmentmentioning

confidence: 99%

“…The most definitive treatment of glomus tumor is surgical excision [17,20,33,35]. Treatments other than this do little to ease the pain.…”

Section: Discussion and Treatmentmentioning

confidence: 99%

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Thigh Pain of 5 Years’ Duration in a 48-year-old Man

Sraj

Khoury

Afeiche

et al. 2008

Clin Orthop Relat Res

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A 48-year-old man presented to his primary physician with pain localized to the medial region of the left knee of 6 months' duration. The physical examination was normal. His medical history was unremarkable. He was treated empirically with nonsteroidal antiinflammatory medications and physiotherapy without relief. After 3 months of continuing pain, he was referred to an orthopaedic surgeon who ordered an MRI scan which was interpreted as normal. The patient was maintained on symptomatic treatment for several more months with no substantial improvement. The patient continued to endure the pain and utilise symptomatic treatment for the following couple of years. Three years after initial presentation, he obtained a second orthopaedic opinion and had another MRI scan. The examination was again normal and the MRI interpreted as normal. The patient was maintained on symptomatic treatment with no improvement. Throughout he had no constitutional symptoms.The patient presented to our clinic 5 years after his pain first developed. Physical examination of the knee was normal. There was no instability, no joint line tenderness, no crepitation, and full range of motion. He had considerable atrophy and weakness of the quadriceps muscle. Physical examination of the hip and the spine were normal. There was an area of exquisite pinpoint tenderness medially above the joint line, overlying the adductor canal (Fig.

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Section: Discussion and Treatmentmentioning

confidence: 99%

Section: Discussion and Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Thigh Pain of 5 Years’ Duration in a 48-year-old Man

Sraj

Khoury

Afeiche

et al. 2008

Clin Orthop Relat Res

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“…Of all hand tumors, 1%-2% are glomus tumors. Multiple glomus tumors are present in 2.3% of the cases [3]. The average age of patients at diagnosis ranges from 30 to 50 years.…”

Section: Introductionmentioning

confidence: 99%

A Case Report: Glomus Tumor Mimicking Orf Infection

2014

J Turk Acad Dermatol

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Observation: Glomus tumor is a rare vascular tumor that is most commonly located in hand and usually of benign nature arising from the vascular and thermoregulatory glomus body of the skin. However, malignant degeneration can sometimes occur. These hamartomas account for 1% to 5% of all soft tissue tumors of the hand and commonly but not exclusively related to nail bed. The classical presentation is severe pain, temperature sensitivity and localised tenderness. The diagnosis is usually made on the basis of clinical history and examination but can be delayed due to nonspecific symptoms and the rarity of disorder. The aim of our report is to describe a glomus tumor presented as orf infection in a man at his hand appearing in terms of clinical presentation and localization.

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“…The majority of these tumors are small red blue nodules that occur in the dermis or subcutis of the distal extremities, particularly in the subungual region, the hand, the wrist and the foot. A long history of pain especially with exposure to cold or minor tactile stimulation is characteristic (3)(4)(5). Although the features of the tumor are distinctive, diagnosis can be occasionally conflicting because of unusual features such as large size, deep soft tissue or visceral location, infiltrative growth pattern, pleomorphism and mitotic activity (6,7).…”

Section: Introductionmentioning

confidence: 99%

Symplastic glomus tumor

Kabukçuoğlu¹,

Özkayalar²,

Sakiz³

et al. 2013

TJPATH

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Glomus tumors showing nuclear pleomorphism without any other malignant features have been defined as symplastic glomus tumors. This type of glomus tumor is rarely encountered. Another case of symplastic glomus tumor is described in this study. A 37-year-old woman referred to the hospital with the complaint of a palpable tender nodule on the fourth finger tip of her left hand. The lesion had been present for about a year and aggravation of tenderness upon cold exposure was conspicuous. It was a 0.5 cm well circumscribed lesion with round to cuboidal epithelioid cells showing high grade nuclear pleomorphism. nests of cells more uniform in shape and showing punched out nucleus representative of typical glomus tumor could also be observed. Immunohistochemical study showed expression of smooth muscle actin, caldesmon and vimentin. Ki-67 labeling index was undetectable. Investment of tumor cells was shown by type IV collagen. In contrast to its atypical cellular morphology, symplastic glomus tumor clinically behaves benign, and it is important to differentiate it from malignant glomus tumor as well as other primary or metastatic malignant tumors.

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Glomus tumour: An analysis of 43 patients and review of the literature

Abstract: Glomus tumours are hamartomas derived from the normal glomus body. A total of 43 glomus tumours have been seen over the past 18 years, and are reviewed. Their clinical presentations and pathology are analysed and the continuing difficulty in diagnosis is examined.

Cited by 102 publications

References 12 publications

Thigh Pain of 5 Years’ Duration in a 48-year-old Man

Thigh Pain of 5 Years’ Duration in a 48-year-old Man

A Case Report: Glomus Tumor Mimicking Orf Infection

Symplastic glomus tumor

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