Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

Abstract

American Cancer Society; Centers for Disease Control and Prevention; Swiss Re; Swiss Cancer Research foundation; Swiss Cancer League; Institut National du Cancer; La Ligue Contre le Cancer; Rossy Family Foundation; US National Cancer Institute; and the Susan G Komen Foundation.

Ginsenoside 20(S)-Rg3 Prevents PKM2-Targeting miR-324-5p from H19 Sponging to Antagonize the Warburg Effect in Ovarian Cancer Cells

“…The estimated new cases of ovarian cancer are 22,240, and the estimated deaths are 14, 070, which is 5% of deaths of females in the United States [1]. The 5-year survival has long been less than 50% in most countries [2]. Chemotherapy is the main adjuvant therapy for EOC, however, its efficacy is frequently impaired by occurrence of chemoresistance and adverse reaction [3].…”

Lung cancer

“…Outcomes are among the poorest of all tumour types, with five year survival of 10-20% 2. Survival is hugely influenced by stage at diagnosis, with five year survival varying from 92% to 0% for the earliest and latest stages respectively 3.…”

Healthcare outcomes and quality in the NHS: how do we compare and how might the NHS improve?

“…In the CONCORD study of global trends, five year cancer survival in the UK was below that of many other European countries (table 2 shows figures for colon cancer) 9…”