Global Risk Scores and Exercise Testing for Predicting All-Cause Mortality in a Preventive Medicine Program

Utility of graded exercise tolerance tests for prediction of cardiovascular mortality in old age: The Rancho Bernardo Study

“…These observations confirm previous reports that ChI is a good predictor of cardiac death and all-cause mortality(19), and abnormal HRR provides prognostic information for global mortality(20). Myers and colleagues reported that patients exhibiting both ChI and abnormal HRR have more than a four-fold risk of cardiovascular mortality(15).…”

Utility of graded exercise tolerance tests for prediction of cardiovascular mortality in old age: The Rancho Bernardo Study

“…These observations confirm previous reports that ChI is a good predictor of cardiac death and all-cause mortality(19), and abnormal HRR provides prognostic information for global mortality(20). Myers and colleagues reported that patients exhibiting both ChI and abnormal HRR have more than a four-fold risk of cardiovascular mortality(15).…”

Screening for Cardiovascular Disease Risk With Resting or Exercise Electrocardiography

“…Results of the included studies are shown in Figure 4 and Figure 5, and in eTable 5 and eFigures 1 and 2 in the Supplement. All 3 of the studies reporting discrimination for the addition of exercise ECG variables to traditional risk factors reported small absolute improvements in AUC or C statistics (0.02-0.03). None of the studies reported CIs, and only 1 reported a P value; that value indicated no statistically significant difference between models ( P = .3) .…”

“…Of the 14 included studies for KQ2, 5 fair-quality cohort studies (9582 participants) evaluated exercise ECG (Table 2). All participants were from cardiology or prevention centers in hospitals. Four of the studies reported that all participants were asymptomatic; 1 reported that 16.5% had atypical chest pain symptoms and had undergone both coronary artery calcium scoring and single-photon emission computed tomography for “clinically indicated reasons.” Mean baseline FRS score was 10.8 to 12.3 in studies reporting it .…”

Heart Rate Recovery and Risk of Cardiovascular Events and All‐Cause Mortality: A Meta‐Analysis of Prospective Cohort Studies

“…Our initial search identified 1049 potentially relevant citations, and a total of 9 articles met the inclusion criteria and were included in the analysis (Figure ) . Among these articles, 5 provided results for cardiovascular events .…”

“…Among these articles, 5 provided results for cardiovascular events . Since 1 article reported sex‐stratified results on all‐cause mortality, the number of studies for all‐cause mortality was 9 (from 8 articles) …”

Utility of graded exercise tolerance tests for prediction of cardiovascular mortality in old age: The Rancho Bernardo Study

“…These observations confirm previous reports that ChI is a good predictor of cardiac death and all-cause mortality(19), and abnormal HRR provides prognostic information for global mortality(20). Myers and colleagues reported that patients exhibiting both ChI and abnormal HRR have more than a four-fold risk of cardiovascular mortality(15).…”

Screening for Cardiovascular Disease Risk With Resting or Exercise Electrocardiography

“…Results of the included studies are shown in Figure 4 and Figure 5, and in eTable 5 and eFigures 1 and 2 in the Supplement. All 3 of the studies reporting discrimination for the addition of exercise ECG variables to traditional risk factors reported small absolute improvements in AUC or C statistics (0.02-0.03). None of the studies reported CIs, and only 1 reported a P value; that value indicated no statistically significant difference between models ( P = .3) .…”

“…Of the 14 included studies for KQ2, 5 fair-quality cohort studies (9582 participants) evaluated exercise ECG (Table 2). All participants were from cardiology or prevention centers in hospitals. Four of the studies reported that all participants were asymptomatic; 1 reported that 16.5% had atypical chest pain symptoms and had undergone both coronary artery calcium scoring and single-photon emission computed tomography for “clinically indicated reasons.” Mean baseline FRS score was 10.8 to 12.3 in studies reporting it .…”

Heart Rate Recovery and Risk of Cardiovascular Events and All‐Cause Mortality: A Meta‐Analysis of Prospective Cohort Studies

“…Our initial search identified 1049 potentially relevant citations, and a total of 9 articles met the inclusion criteria and were included in the analysis (Figure ) . Among these articles, 5 provided results for cardiovascular events .…”

“…Among these articles, 5 provided results for cardiovascular events . Since 1 article reported sex‐stratified results on all‐cause mortality, the number of studies for all‐cause mortality was 9 (from 8 articles) …”

Utility of graded exercise tolerance tests for prediction of cardiovascular mortality in old age: The Rancho Bernardo Study

“…These observations confirm previous reports that ChI is a good predictor of cardiac death and all-cause mortality(19), and abnormal HRR provides prognostic information for global mortality(20). Myers and colleagues reported that patients exhibiting both ChI and abnormal HRR have more than a four-fold risk of cardiovascular mortality(15).…”

Screening for Cardiovascular Disease Risk With Resting or Exercise Electrocardiography

“…Results of the included studies are shown in Figure 4 and Figure 5, and in eTable 5 and eFigures 1 and 2 in the Supplement. All 3 of the studies reporting discrimination for the addition of exercise ECG variables to traditional risk factors reported small absolute improvements in AUC or C statistics (0.02-0.03). None of the studies reported CIs, and only 1 reported a P value; that value indicated no statistically significant difference between models ( P = .3) .…”

“…Of the 14 included studies for KQ2, 5 fair-quality cohort studies (9582 participants) evaluated exercise ECG (Table 2). All participants were from cardiology or prevention centers in hospitals. Four of the studies reported that all participants were asymptomatic; 1 reported that 16.5% had atypical chest pain symptoms and had undergone both coronary artery calcium scoring and single-photon emission computed tomography for “clinically indicated reasons.” Mean baseline FRS score was 10.8 to 12.3 in studies reporting it .…”

Heart Rate Recovery and Risk of Cardiovascular Events and All‐Cause Mortality: A Meta‐Analysis of Prospective Cohort Studies

“…Our initial search identified 1049 potentially relevant citations, and a total of 9 articles met the inclusion criteria and were included in the analysis (Figure ) . Among these articles, 5 provided results for cardiovascular events .…”

“…Among these articles, 5 provided results for cardiovascular events . Since 1 article reported sex‐stratified results on all‐cause mortality, the number of studies for all‐cause mortality was 9 (from 8 articles) …”