2020
DOI: 10.1001/jamaoncol.2019.6716
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Abstract: Global Retinoblastoma Study Group IMPORTANCE Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale.OBJECTIVES To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variab… Show more

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Cited by 191 publications
(108 citation statements)
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“…An important reason for contrasting eye salvage has been that many lower-income countries lack access to advanced, end organ chemotherapy typically employed in a HIC. 3,4,43,44…”
Section: Cumulative Proportion Of Avoiding Local Treatment Failure Bymentioning
confidence: 99%
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“…An important reason for contrasting eye salvage has been that many lower-income countries lack access to advanced, end organ chemotherapy typically employed in a HIC. 3,4,43,44…”
Section: Cumulative Proportion Of Avoiding Local Treatment Failure Bymentioning
confidence: 99%
“…Retinoblastoma (RB), the most frequent primary pediatric eye cancer, has been the second most common intraocular cancer worldwide. [1][2][3] Patient prognosis has depended on early diagnosis and prompt treatment. 1 Advances in chemotherapy and local treatment have resulted in improved globe salvage and reductions in disease-specific mortality.…”
Section: Introductionmentioning
confidence: 99%
See 3 more Smart Citations