Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

The Burden of Early-Onset Colorectal Cancer and Its Risk Factors from 1990 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019

“…In line with the GBD 2019 Colorectal Cancer Collaborator study [ 9 ], the present study found a substantial rise in the EoCRC incidence rate, particularly in the high SDI region, from 1990 to 2019. Globally, diets low in milk (16%), smoking (13%), diets low in calcium (13%), and alcohol use (10%) were the leading risk factors for the whole CRC population in 2019.…”

“…Based on the up-to-date data from the Global Burden of Disease (GBD) Study 2019, [ 6 , 7 , 8 ] we systematically reported the incidence, deaths, and DALYs of EoCRC and its risk factors at the global, regional, and national levels in relation to year, age, sex, geographic location, and sociodemographic index (SDI) from 1990 to 2019. Although the burden of CRC and its risk factors based on GBD 2019 have been well estimated [ 9 , 10 , 11 , 12 ], there is no one study focusing specifically on EoCRC. To our knowledge, this study is the first to investigate the burden of EoCRC and its risk factors based on the latest data from the GBD 2019.…”

Burden and trend of colorectal cancer in 54 countries of Africa 2010–2019: a systematic examination for Global Burden of Disease

“…According to GLOBACAN reported in 2020, colorectal cancer was responsible for more than 1.9 million new incident cases and 0.94 million deaths, making third and second rank for overall cancer incidence and mortality globally [ 2 ]. Global incidence cases of CRC doubled or more than doubled in 157 of 204 countries, and mortality due to CRC doubled of more doubled in 129 of 204 countries, pronounced increases were observed in low and Middle SDI countries from 1990 to 2019 [ 3 ]. Due to the rapid rising of global population size, aging and human economic development, burden of CRC is predicted to be 2.2 million new cases and 1.1 million cancer deaths by 2030 [ 4 ] and 3.2 million new incidence cases in 2040 [ 5 ].…”

Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019

“…Through the detection and removal of malignant tumors at an early stage, death rates were not raised markedly. Unhealthy diet, smoking, alcohol consumption, high BMI, and high fasting plasma glucose have always influenced the incidence and prognosis of colon and rectum cancer, and this is also reflected in the fact that the incidence of males has risen faster than that of females in recent years (34,35). However, it should be emphasized that an important attributing factor for females might be a dietary risk, for which managers are advised to take the distinction into account (36).…”