2019
DOI: 10.1016/s1474-4422(18)30403-4
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Abstract: SummaryBackgroundThe number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A successful response to these challenges requires an accurate understanding of the dementia disease burden. We aimed to present the first detailed analysis of the global prevalence, mortality, and overall burden of dementia as captured by the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, and highlight the most important m… Show more

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Cited by 1,556 publications
(832 citation statements)
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References 38 publications
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“…Rationale Approximately 43.8 million people lived with dementia worldwide in the year 2016 (Nichols et al, 2019) and this number is projected to increase to 115.5 million people by 2050 (Prince et al, 2013). The global economic cost of dementia is estimated to surpass US$2 trillion per year by 2030 (Wimo et al, 2017).…”
Section: Introductionmentioning
confidence: 99%
“…Rationale Approximately 43.8 million people lived with dementia worldwide in the year 2016 (Nichols et al, 2019) and this number is projected to increase to 115.5 million people by 2050 (Prince et al, 2013). The global economic cost of dementia is estimated to surpass US$2 trillion per year by 2030 (Wimo et al, 2017).…”
Section: Introductionmentioning
confidence: 99%
“…Despite the high prevalence of AD in the current aging society (Nichols et al, 2019), the exact proportion of frontal variants of AD is largely unknown. The description of this rare AD phenotype has been limited to case reports and small series (Alladi et al, 2007;Johnson, Head, Kim, Starr, & Cotman, 1999;Ossenkoppele et al, 2015;Scialo et al, 2016;de Souza et al, 2013).…”
Section: Discussionmentioning
confidence: 99%
“…By 2050, 131.5 million people worldwide will be living with dementia, demonstrating a 204% increase since 2017 . A recent Lancet report stated that until prevention or curative breakthroughs are made dementia will constitute an increasing challenge to health care systems worldwide. It is estimated that 25% of hospital beds are used by people with dementia, a total of 3.2 million bed days a year in the UK, and in the United States, people with dementia have twice as many hospital stays per year as other older people .…”
Section: Introductionmentioning
confidence: 99%