2017
DOI: 10.1016/s0140-6736(17)32152-9
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Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016

Abstract: SummaryBackgroundMonitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition with changes in development and where local patterns deviate from these trends.MethodsWe estimated cause-specific… Show more

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Cited by 3,610 publications
(2,227 citation statements)
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“…However, despite numerous phase I and II clinical trials, there is ongoing controversy as to the ideal patient population for cell treatment. Considering that ischemic cardiomyopathy (ICM) is a leading cause of death worldwide and nonischemic dilated cardiomyopathy (DCM) is a progressive disorder with a high morbidity and mortality, often culminating in heart transplant, novel regenerative therapies are required to treat both underlying causes of left ventricular (LV) dysfunction and heart failure (HF) 3. Bone marrow–derived human mesenchymal stem cells (MSCs) are particularly promising because they possess antifibrotic, proangiogenic, and immunomodulatory properties that stimulate repair of damaged tissues 4.…”
Section: Introductionmentioning
confidence: 99%
“…However, despite numerous phase I and II clinical trials, there is ongoing controversy as to the ideal patient population for cell treatment. Considering that ischemic cardiomyopathy (ICM) is a leading cause of death worldwide and nonischemic dilated cardiomyopathy (DCM) is a progressive disorder with a high morbidity and mortality, often culminating in heart transplant, novel regenerative therapies are required to treat both underlying causes of left ventricular (LV) dysfunction and heart failure (HF) 3. Bone marrow–derived human mesenchymal stem cells (MSCs) are particularly promising because they possess antifibrotic, proangiogenic, and immunomodulatory properties that stimulate repair of damaged tissues 4.…”
Section: Introductionmentioning
confidence: 99%
“…In 2016, 17.6 million deaths were caused by CVD; the death from cardiovascular diseases increased by 14.5% from 2006 and 2016 1. Previous epidemiological studies suggest that greater tea consumption is related to lower cardiovascular disease (CVD) risk2, 3; 1 to 3 or more cups of green or black tea per day is associated with a 20% to 30% risk reduction in stroke and CVD 3, 4.…”
Section: Introductionmentioning
confidence: 99%
“…Nevertheless, national levels and trends of mortality from external causes in LMICs are currently extrapolated from these partial data sources (Naghavi et al 2017;Sanghavi, Bhalla, and Das 2009). The resulting estimates may be unreliable because they may omit some deaths, or inaccurately reclassify deaths attributed to unknown causes as injury-related (Bhalla and Harrison 2015).…”
Section: Introductionmentioning
confidence: 99%