Global estimates of human papillomavirus vaccination coverage by region and income level: a pooled analysis

Bruni, Laia; Díaz, Mireia; Barrionuevo-Rosas, Leslie; Herrero, Rolando; Bray, Freddie; Bosch, F. Xavier; Sanjosé, Sílvia de; Castellsagué, Xavier

doi:10.1016/s2214-109x(16)30099-7

Cited by 620 publications

(546 citation statements)

References 24 publications

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“…At the same time, the prophylactic HPV vaccination reduces the incidence of HPV infection, assuming a reduction in the incidence of HPV-associated cancers (20). Prophylactic HPV vaccination is part of the individual immunisation schedule in many countries, although the country-specific performance varies considerably (21). Besides the effect on the uterine cervix, the quadrivalente HPV vaccine was demonstrated to prevent persistent anal HPV infection and anal intraepithelial lesions (22).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations

et al. 2017

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Abstract. Infection with certain types of human papillomavirus (HPV) has been associated with the development of cervical and anal cancer. Worldwide, the incidence of anal cancer has increased markedly. The present study aimed to evaluate the prevalence of HPV infection of the uterine cervix and anal canal in human immunodeficiency virus (HIV)-and non-HIV-infected risk populations. Cervical and anal HPV swabs and cytology samples were collected from 287 patients at the University Hospital of Munich, Germany between 2011 and 2013. Patients were divided into HIV-negative controls (G1) and two risk groups, including HIV-negative patients with cytological abnormalities of the cervix (G2) and HIV-infected patients (G3). Data, including clinical parameters, were analysed. The risk groups had significantly more positive results for HPV in the anus (71.03 and 83.15% for G2 and G3, respectively), as compared with G1. The predominant HPV genotypes found in the anus were high-risk HPV genotypes, which were significantly correlated with concomittant cervical HPV findings. In the risk groups, a significant association between the cytological findings and HPV detection in the cervix was found, while the results of the anus revealed no significance. The results of the present study suggested that the prevalence of HPV infection in the anal canal of risk populations is high. Furthermore, patients with abnormal cervical cytology results and HIV-infected women, irrespective of their individual cervical findings, may have a risk of concomittant anal high-risk HPV infection. Based on the predominant HPV genotypes found in the study, HPV vaccination could reduce the incidence of anal cancer. Nevertheless, high-risk patients should be intensively screened for anal squamous intraepithelial abnormalities to avoid invasive cancer stages.

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Section: Discussionmentioning

confidence: 99%

Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations

et al. 2017

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“…In addition to preventing EGW and RRP, it is biologically plausible that 2vHPV, 4vHPV, and 9vHPV would protect against some HNSCC [7,12]. The average female Latin American and Caribbean HPV vaccination coverage is 19% [15]. Low HPV vaccination rates mean that CC mortality, and the incidence of anal, cervical, oropharyngeal, penile, vaginal, and vulvar cancers, EGW, HNSCC, and RRP will not decline as rapidly as possible.…”

Section: Introductionmentioning

confidence: 99%

Attitudes Towards Human Papilloma Virus Vaccination in the Latin American Andean Region

Nwanodi¹

2017

Gynecol Obstet (Sunnyvale)

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This commentary explores the distribution of human papilloma virus (HPV) and HPV-related diseases, and factors affecting attitudes towards HPV, HPV-related diseases, and HPV vaccination in the Latin American Andean region. Lack of knowledge of HPV, known negative attitudes or incorrect assumptions about HPV, HPV-related diseases, and HPV vaccination provide a basis upon which to develop targeted HPV awareness and preventive health media campaigns. For maximal effect, media campaigns should use the internet, radio, and television to address health care providers, parents, and students. Additional programming can be developed for clinics to use in-house with their clients. Ministries of Education, Finance, and Health all have roles to play to increase national HPV, HPV-related diseases, and HPV vaccination awareness.

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“…HPV vaccination, the first available against a cancer, is now well established in most European countries [3]. Originally reimbursed only for girls in Europe, it has since been extended to boys in a few countries such as Austria and Italy.…”

Section: Hpv Vaccinationmentioning

confidence: 99%

Pricing of HPV Vaccines in Europe: Back to the Future?

Garattini

Padula

2018

Appl Health Econ Health Policy

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Global estimates of human papillomavirus vaccination coverage by region and income level: a pooled analysis

Abstract: PATH, Instituto de Salud Carlos III, and Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR).

Cited by 620 publications

References 24 publications

Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations

Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations

Attitudes Towards Human Papilloma Virus Vaccination in the Latin American Andean Region

Pricing of HPV Vaccines in Europe: Back to the Future?

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