2007
DOI: 10.1016/j.idc.2007.01.010
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Abstract: Although intravenous drug use is the major route of transmission in several countries, sexual transmission is the dominant mode of HIV spread globally, with a concomitant epidemic in infants borne to HIV-infected mothers. The HIV epidemic varies substantially from one geographic area to another, and three broad epidemic categories describe the diversity of features observed globally: low epidemic settings, centrzated epidemics, and generalized epidemics. The introduction of highly active antiretroviral therapy… Show more

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Cited by 21 publications
(7 citation statements)
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“…The same nations, especially those in Africa, also struggle with significant burden due to HIV/AIDS, disproportionately affecting women[44,45]. The need for clear, evidence-based screening and treatment guidelines is especially imperative in these settings as hundreds of thousands of HIV-infected women are now accessing HAART and are starting to live longer in a moderately immunocompetent state.…”
Section: Resultsmentioning
confidence: 99%
“…The same nations, especially those in Africa, also struggle with significant burden due to HIV/AIDS, disproportionately affecting women[44,45]. The need for clear, evidence-based screening and treatment guidelines is especially imperative in these settings as hundreds of thousands of HIV-infected women are now accessing HAART and are starting to live longer in a moderately immunocompetent state.…”
Section: Resultsmentioning
confidence: 99%
“…An estimated 6.4 million people were living with HIV infection in South Africa in 2012[1], making South Africa the country with the largest absolute number of people living with HIV worldwide and nearly one-sixth of the burden worldwide[2]. The government of South Africa has made a strong commitment to providing HIV counseling and testing (HCT) to all individuals, and provided HCT to approximately 9 million South Africans between April 2012 and March 2013[3].…”
Section: Introductionmentioning
confidence: 99%
“…However, current antiviral drugs do not eradicate the virus, and prolonged treatment can have serious side effects and select drug-resistant viral strains (1). In addition, millions of new infections occur worldwide each year (2,3). Continued efforts toward the discovery of new antiviral strategies therefore remain imperative.…”
Section: Introductionmentioning
confidence: 99%