Global burden of female breast cancer and its association with socioeconomic development status, 1990–2044

Abstract

BackgroundBreast cancer is a widespread disease in women worldwide.AimWe aimed to explore the global epidemiological trends of female breast cancer (FBC) between 1990 and 2044.Methods and ResultsDisease burden, population, and socio‐demographic index (SDI) data were obtained from the Global Health Data Exchange (GHDx) database. We analyzed temporal trends, age differences, risk factors, and geographic patterns of FBC disease burden globally and explored the association between age‐standardized incidence rate (ASIR) of FBC and SDI. Bayesian age‐period‐cohort model was also performed to predict the changes in FBC incidence worldwide from 2020 to 2044. First, the global ASIR of FBC increased by 14.31% from 1990 to 2019 (95% Uncertainty Interval 4.75% to 23.98%). The death rate presented a falling trend. Second, alcohol use is the most‐highlighted risk factor for FBC in some high‐income regions such as Europe. A high fasting plasma glucose levels is the most prominent risk factor for FBC in Latin America and Africa. Third, the ASIR of the FBC increases with the SDI. Fourth, the incidence is expected to increase faster among women aged 35–60 years and fastest for those aged 50–54 years from 2020 to 2044. Countries with a high incidence of FBC that is expected to increase significantly include Barbados, Burkina Faso, Senegal, Monaco, Lebanon, Togo, and Uganda.ConclusionThe disease burden of FBC varies worldwide; the findings suggest attaching importance to the control of middle and low‐middle SDI regions. Public health as well as cancer prevention experts should pay more attention to regions and populations at an increased risk of developing FBC, focusing on their prevention and rehabilitation while conducting further epidemiological studies to investigate the risk factors of their increase.

Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO international clinical trial register database

“…This change in DALYs from female breast cancer can be attributed to the following factors. Firstly, alcohol consumption was the greatest distributor of breast cancer DALYs and mortality ( 19 , 26 ). Studies which demonstrated the use of alcohol declined significantly in the past three decades especially in the high and the high middle SDI countries, while increased in most developing countries.…”

Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO international clinical trial register database

“…This change in DALYs from female breast cancer can be attributed to the following factors. Firstly, alcohol consumption was the greatest distributor of breast cancer DALYs and mortality ( 19 , 26 ). Studies which demonstrated the use of alcohol declined significantly in the past three decades especially in the high and the high middle SDI countries, while increased in most developing countries.…”

Age-Period-Cohort Analysis on the Burden of Gastrointestinal Cancers in China: Trends, Risk Factors, and Predictions

“…All the figures were created using the ggplot2 package in R (version 4.4.2). The selection of analytical tools was based on their methodological robustness and widespread validation in epidemiological research [ 17 , 18 , 19 ].…”

Bridging racial and ethnic disparities in cancer research

“…Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60. 1 Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women. They were younger at diagnosis, had larger tumors, and had more axillary lymph nodes involved.…”

“…It is found that incidence rates correlate with sociodemographic factors, such as alcohol consumption in high‐income regions, such as Europe, and high levels of fasting plasma glucose in Latin America and Africa. Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60 1 . Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women.…”

Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO international clinical trial register database

“…This change in DALYs from female breast cancer can be attributed to the following factors. Firstly, alcohol consumption was the greatest distributor of breast cancer DALYs and mortality ( 19 , 26 ). Studies which demonstrated the use of alcohol declined significantly in the past three decades especially in the high and the high middle SDI countries, while increased in most developing countries.…”

Age-Period-Cohort Analysis on the Burden of Gastrointestinal Cancers in China: Trends, Risk Factors, and Predictions

“…All the figures were created using the ggplot2 package in R (version 4.4.2). The selection of analytical tools was based on their methodological robustness and widespread validation in epidemiological research [ 17 , 18 , 19 ].…”

Bridging racial and ethnic disparities in cancer research

“…Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60. 1 Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women. They were younger at diagnosis, had larger tumors, and had more axillary lymph nodes involved.…”

“…It is found that incidence rates correlate with sociodemographic factors, such as alcohol consumption in high‐income regions, such as Europe, and high levels of fasting plasma glucose in Latin America and Africa. Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60 1 . Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women.…”

Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021 and WHO international clinical trial register database

“…This change in DALYs from female breast cancer can be attributed to the following factors. Firstly, alcohol consumption was the greatest distributor of breast cancer DALYs and mortality ( 19 , 26 ). Studies which demonstrated the use of alcohol declined significantly in the past three decades especially in the high and the high middle SDI countries, while increased in most developing countries.…”

Age-Period-Cohort Analysis on the Burden of Gastrointestinal Cancers in China: Trends, Risk Factors, and Predictions

“…All the figures were created using the ggplot2 package in R (version 4.4.2). The selection of analytical tools was based on their methodological robustness and widespread validation in epidemiological research [ 17 , 18 , 19 ].…”

Bridging racial and ethnic disparities in cancer research

“…Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60. 1 Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women. They were younger at diagnosis, had larger tumors, and had more axillary lymph nodes involved.…”

“…It is found that incidence rates correlate with sociodemographic factors, such as alcohol consumption in high‐income regions, such as Europe, and high levels of fasting plasma glucose in Latin America and Africa. Through 2044, future projections predict a rapid rise in incidence, particularly among women aged 35–60 1 . Additionally, Sassi et al found that Tunisian and Algerian women with BC had significant differences in their clinical and histopathological characteristics compared with Western women.…”