Abstract:Glioblastoma multiforme (GBM) is one of the deadliest and most aggressive cancers, remarkably resilient to current therapeutic treatments. Here, we report in vivo studies of GBM treatments based on photo-nanotherapeutics able to induce synergistic killing mechanisms. Core-shell nanoparticles have been weaponized by combining the photophysical properties of an Ir(III) complex -a new generation PDT agent -with the thermo-plasmonic effects of resonant gold nanospheres. To investigate the damages induced in GBM tr… Show more
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