“…Several promising automatic, semi-automatic and interactive approaches were evaluated, 12 including atlas-based segmentation techniques [13][14][15] . Because of the excellent depiction of the prostate and surrounding anatomy, the high signal-to-noise ratio (SNR), and high spatial resolution, 12,16,17 T2-weighted MRI is the sequence of choice for building a prostate atlas 12,[18][19][20][21][22] . More recently, several studies provide also segmentation of the prostate zonal structures 21,[23][24][25] The presented approaches vary from model-based 26,27 , to atlasbased segmentation 15,[18][19][20][21]28 The goal of this work is to implement a robust procedure for prostate and prostate zones segmentation in a clinical imaging platform MIM (MIM Software Inc, Cleveland, OH, USA).…”