Giant Cerebral Capillary Telangiectasis in an Infant

Abstract

The authors describe an unusual and unique case of a giant capillary telangiectasis of the right frontal lobe encountered in a 10-month-old child. The patient presented with progressive neurologic symptoms mimicking a brain tumor. The lesions was resected in toto with good clinical results.

Symptomatic large or giant capillary telangiectasias: management and outcome in 5 cases

“…In the previous literature, surgical management of giant and large BCTs has been reported to have favorable outcomes. 4,6,17,18,22,24,25,27 In our case series, all lesions were symptomatic and their surgical removal lesions resulted in significant symptom relief.…”

“…Favorable outcomes without significant neurological deficits were documented in most of these cases. 4,6,14,17,18,24 In our series, patients with intractable seizures were seizure free, and the patient with episodic visual disturbances regained her vision gradually. Conservative therapy should be recommended after surgery to reach optimal control of the symptoms.…”

“…8,12,25 Standard management is undefined for large or giant BCTs. 7,12,20,24,27,29 To our knowledge, the current study presents the largest case series of large BCTs ever reported. We analyzed the radiological findings, histopathological characteristics, clinical presentation, and management in 5 symptomatic, unusually large BCTs (mean diameter 5.06 cm, range 1.8-8 cm).…”

“…Only 10 symptomatic cases with 3 diffuse BCTs have been reported in the English-language literature of more than 200 BCTs. 12,20,24,27,29 Large BCTs have a much higher risk of causing uncontrolled bleeding and severe neurological deficits and even death if left untreated. 2,12,13,21,22 Therefore, large BCTs should be managed with special caution.…”

“…9,27,29 In addition, development of an aggressive form with increased risk of bleeding from giant or diffuse BCTs has also been reported. 24,29 In the existing reports of 10 cases of symptomatic large BCTs, 8 underwent resection. Favorable outcomes without significant neurological deficits were documented in most of these cases.…”

Symptomatic large or giant capillary telangiectasias: management and outcome in 5 cases

“…In the previous literature, surgical management of giant and large BCTs has been reported to have favorable outcomes. 4,6,17,18,22,24,25,27 In our case series, all lesions were symptomatic and their surgical removal lesions resulted in significant symptom relief.…”

“…Favorable outcomes without significant neurological deficits were documented in most of these cases. 4,6,14,17,18,24 In our series, patients with intractable seizures were seizure free, and the patient with episodic visual disturbances regained her vision gradually. Conservative therapy should be recommended after surgery to reach optimal control of the symptoms.…”

“…8,12,25 Standard management is undefined for large or giant BCTs. 7,12,20,24,27,29 To our knowledge, the current study presents the largest case series of large BCTs ever reported. We analyzed the radiological findings, histopathological characteristics, clinical presentation, and management in 5 symptomatic, unusually large BCTs (mean diameter 5.06 cm, range 1.8-8 cm).…”

“…Only 10 symptomatic cases with 3 diffuse BCTs have been reported in the English-language literature of more than 200 BCTs. 12,20,24,27,29 Large BCTs have a much higher risk of causing uncontrolled bleeding and severe neurological deficits and even death if left untreated. 2,12,13,21,22 Therefore, large BCTs should be managed with special caution.…”

“…9,27,29 In addition, development of an aggressive form with increased risk of bleeding from giant or diffuse BCTs has also been reported. 24,29 In the existing reports of 10 cases of symptomatic large BCTs, 8 underwent resection. Favorable outcomes without significant neurological deficits were documented in most of these cases.…”

Symptomatic large or giant capillary telangiectasias: management and outcome in 5 cases

“…In the previous literature, surgical management of giant and large BCTs has been reported to have favorable outcomes. 4,6,17,18,22,24,25,27 In our case series, all lesions were symptomatic and their surgical removal lesions resulted in significant symptom relief.…”

“…Favorable outcomes without significant neurological deficits were documented in most of these cases. 4,6,14,17,18,24 In our series, patients with intractable seizures were seizure free, and the patient with episodic visual disturbances regained her vision gradually. Conservative therapy should be recommended after surgery to reach optimal control of the symptoms.…”

“…8,12,25 Standard management is undefined for large or giant BCTs. 7,12,20,24,27,29 To our knowledge, the current study presents the largest case series of large BCTs ever reported. We analyzed the radiological findings, histopathological characteristics, clinical presentation, and management in 5 symptomatic, unusually large BCTs (mean diameter 5.06 cm, range 1.8-8 cm).…”

“…Only 10 symptomatic cases with 3 diffuse BCTs have been reported in the English-language literature of more than 200 BCTs. 12,20,24,27,29 Large BCTs have a much higher risk of causing uncontrolled bleeding and severe neurological deficits and even death if left untreated. 2,12,13,21,22 Therefore, large BCTs should be managed with special caution.…”

“…9,27,29 In addition, development of an aggressive form with increased risk of bleeding from giant or diffuse BCTs has also been reported. 24,29 In the existing reports of 10 cases of symptomatic large BCTs, 8 underwent resection. Favorable outcomes without significant neurological deficits were documented in most of these cases.…”

Symptomatic large or giant capillary telangiectasias: management and outcome in 5 cases

“…In the previous literature, surgical management of giant and large BCTs has been reported to have favorable outcomes. 4,6,17,18,22,24,25,27 In our case series, all lesions were symptomatic and their surgical removal lesions resulted in significant symptom relief.…”

“…Favorable outcomes without significant neurological deficits were documented in most of these cases. 4,6,14,17,18,24 In our series, patients with intractable seizures were seizure free, and the patient with episodic visual disturbances regained her vision gradually. Conservative therapy should be recommended after surgery to reach optimal control of the symptoms.…”

“…8,12,25 Standard management is undefined for large or giant BCTs. 7,12,20,24,27,29 To our knowledge, the current study presents the largest case series of large BCTs ever reported. We analyzed the radiological findings, histopathological characteristics, clinical presentation, and management in 5 symptomatic, unusually large BCTs (mean diameter 5.06 cm, range 1.8-8 cm).…”

“…Only 10 symptomatic cases with 3 diffuse BCTs have been reported in the English-language literature of more than 200 BCTs. 12,20,24,27,29 Large BCTs have a much higher risk of causing uncontrolled bleeding and severe neurological deficits and even death if left untreated. 2,12,13,21,22 Therefore, large BCTs should be managed with special caution.…”

“…9,27,29 In addition, development of an aggressive form with increased risk of bleeding from giant or diffuse BCTs has also been reported. 24,29 In the existing reports of 10 cases of symptomatic large BCTs, 8 underwent resection. Favorable outcomes without significant neurological deficits were documented in most of these cases.…”