Giant cell myocarditis causing refractory ventricular tachycardia in a pediatric patient

Panchal, Apurva; Okojie, Obehioye; Slagle, Brittany; Tawfik, Ossama

doi:10.1002/ccr3.1410

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2019

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“…Classic reports of GCM include patients with acute onset heart failure rapidly progressing to cardiogenic shock and death within weeks to months of initial presentation . GCM is often associated with refractory ventricular arrhythmias or other conduction abnormalities . Only 14–29% of patients initially present with VT compared with more than 75% of patients presenting with acutely decompensated heart failure .…”

Section: Discussionmentioning

confidence: 99%

A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support

et al. 2019

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Giant cell myocarditis is a rare but often devastating diagnosis. Advances in cardiac imaging and mechanical circulatory support have led to earlier and more frequent diagnoses and successful management. This disease state has wide variation in acuity of presentation, and consequently, optimal treatment ranging from intensity and type of immunosuppression to mechanical circulatory support is not well defined. The following case describes the management of a patient with an unusual presentation of giant cell myocarditis over a 10 year course of advanced heart failure therapies and immunomodulatory support. This case highlights emerging concepts in the management of giant cell myocarditis including sub‐acute presentations, challenges in diagnosis, and treatment modalities in the modern era.

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Section: Discussionmentioning

confidence: 99%

A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support

et al. 2019

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Giant cell myocarditis causing refractory ventricular tachycardia in a pediatric patient

Abstract: Key Clinical MessageGiant cell myocarditis should be considered in all pediatric patients with refractory ventricular arrhythmia. Endomyocardial biopsy should be obtained to confirm the diagnosis of giant cell myocarditis.

Cited by 1 publication

References 9 publications

A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support

A giant mystery in giant cell myocarditis: navigating diagnosis, immunosuppression, and mechanical circulatory support

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