Gianotti-Crosti syndrome. A review of ten cases not associated with hepatitis B

Combined Vaccination by Measles and Hepatitis B Vaccines: A New Cause of Gianotti-Crosti Syndrome

“…Besides HBV infection, a large number of infectious agents, mostly viruses including EBV, CMV, respiratory syncytial virus and parainfluenza virus have been described as causative (table 1). Preceding immunization is also believed to be an etiological factor for GCS, and the association has been reported several times in the literature [3, 4, 5, 6, 7, 8, 9, 10, 11](table 2). However, in most of these reports there was also concurrent evidence of viral infections [4, 6, 8].…”

An Epidemic of Infantile Papular Acrodermatitis (Gianotti-Crosti Syndrome) due to Epstein-Barr Virus

“…this being the most common causal agent [4,[7][8][9][10] reported in the literature, together with hepatitis B virus [8], PAD clusters are uncommon [3], As the patients were in the same crèche class, two facts could have played impor tant roles: (1) the raised contagiosity of EBV, due to the long and close contacts among the children, and (2) the immunization with diphtheria-tetanus-pcrtussis-polyomyelitis vaccine, administered from 2 to 6 weeks before. Sev eral authors reported that PAD and immunizations are connected [7,9,11]. On the basis of our observations, we consider that PAD may need both a previous immune stim ulation, whatever it may be, and a viral infection.…”

“…cytomegalovirus [5], coxsackievirus [6] and para-influenza virus [7], are associated with PAD. so this term is used to describe all eruptive and acrolocated dermatoses that run a benign and self-healing course in a few weeks (8], sometimes occurring after either immuniza tion or respiratory illness [7,9] or diarrhoea [9].…”

Gianotti-Crosti-Syndrome associated with Epstein-Barr-Virus Infection

“…Eine HBV-Infektion ist nach ihrer Ansicht keine Voraussetzung für die Diagnose, für die insgesamt die Bezeichnung Gianotti-CrostiSyndrom empfohlen wird. Verschiedene Virusinfektionen können der Eruption zugrundeliegen: Am häufigsten Epstein-Barr-Virus (EBV), außerdem Coxsackie-A' und B-Virus, Parvovirus B19, Zytomegalievirus, Parainfluenzavirus, Respiratory-syncytial-Virus und Hepatitis-A-Virus [3,5,7,[10][11][12][14][15][16]. Das Gianotti-Crosti-Syndrom wurde auch als Impffolgereaktion beobachtet [1,4,11,16].…”