Gestational Gigantomastia

Gestational gigantomastia: A case report and brief review of the literature

“…These include idiopathic, juvenile (puberty associated), gestational, and drug induced (most associated with bucillamine and penicillamine administration). 1 , 7 , 8 The pathogenesis of juvenile gigantomastia and GG is still not entirely elucidated. The postulated cause is related to hormonal changes surrounding puberty and pregnancy, which can come in the form of either hormonal excess or hypersensitivity of the breast tissue to normal levels of circulating hormones.…”

“… 8 , 9 The hormones likely implicated are estrogen, progesterone, prolactin, testosterone, and cortisol, and consideration may be given to thyroxine, growth hormone, insulin, and human placental lactogen. 7 , 9 Specifically, with regard to GG, prolactin is the primary hormone to show potential as a target for therapy. 2 , 7 …”

“… 7 , 9 Specifically, with regard to GG, prolactin is the primary hormone to show potential as a target for therapy. 2 , 7 …”

“…Treatment depends mainly on the severity of disease and can range from medical management with bromocriptine to surgical management with reduction mammoplasty or bilateral mastectomy. 1 , 4 , 7 …”

Inferior Pedicle Breast Reduction for the Management of Gestational Gigantomastia: Literature Review and a Case Presentation

“…Complete mastectomy has been the recommended treatment for gigantomastia [2] [18] due to the ability of the condition to recur even after breast reduction. However, the problem of inability to breast feed among pregnant women taking this treatment is very important, especially in developing countries where breast feeding is very common [3] and most people cannot afford baby formula foods.…”