Geospatial Spread of Antimicrobial Resistance, Bacterial and Fungal Threats to Coronavirus Infectious Disease 2019 (COVID-19) Survival, and Point-of-Care Solutions

Kost, Gerald J.

doi:10.5858/arpa.2020-0284-ra

Cited by 14 publications

(7 citation statements)

References 138 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several antimicrobial drugs have lost their effectiveness in recent years and are no longer suitable for treating infections caused by multidrug‐resistant bacteria. In addition, the heavy use of antibiotics is becoming even more critical in the Coronavirus (COVID‐19) pandemic (Kost, 2021; Razzaque, 2020), which could further increase this phenomenon. Faced with this resurgence, it is necessary to explore new therapeutic approaches such as QQ as an innovative strategy to counter the real scourge of antimicrobial resistance.…”

Section: Discussionmentioning

confidence: 99%

Quorum quenching and anti-biofilm activities of halotolerant Bacillus strains isolated in different environments in Algeria

Aichar

Muras

Parga

et al. 2022

Journal of Applied Microbiology

View full text Add to dashboard Cite

Aims The current study aimed to screen Bacillus strains with wide‐spectrum quorum quenching (QQ) activity against N‐acyl‐l‐homoserine lactones (AHLs), helpful in controlling virulence traits in Gram‐negatives, including biofilm formation and also with anti‐biofilm activity against Gram‐positives. Methods and Results A total of 94 halotolerant strains of Bacillus isolated from soil and salt‐lake sediment samples in Algeria were examined for the presence of QQ activity against AHLs, the presence of the aiiA gene, encoding an AHL lactonase enzyme typical of Bacillus spp., antimicrobial and anti‐biofilm activities against Pseudomonas aeruginosa and Streptococcus mutans. Of all strains of Bacillus spp. isolated, 48.9% showed antibacterial activity. In addition, 40% of these isolates showed a positive QQ activity against long‐chain AHLs, of which seven strains presented the aiiA gene. Among the species with broad‐spectrum QQ activity, the cell extract of Bacillus thuringiensis DZ16 showed antibiofilm activity against P. aeruginosa PAO1, reducing 60% using the Amsterdam active attachment (AAA) biofilm cultivation model. In addition, the cell extract of B. subtilis DZ17, also presenting a broad‐spectrum QQ activity, significantly reduced Strep. mutans ATCC 25175 biofilm formations by 63% and 53% in the xCELLigence and the AAA model, respectively, without affecting growth. Strain DZ17 is of particular interest due to its explicit halophilic nature because it can thrive at salinities in the range of 6%–30%. Conclusions B. thuringiensis DZ16 and B. subtilis DZ17 strains have interesting antibacterial, QQ, and anti‐biofilm activities. The high range of salinities accepted by these strains increases their biotechnological potential. This may open up their use as probiotics, the treatment and prevention of conventional and emerging infectious diseases. Significance and Impact of Study The use of safe, economical and effective probiotics is limited to control the infections related to multi‐resistant bacteria. In our study, we provide two promising agents with QQ, anti‐biofilm and antibacterial activities.

show abstract

Section: Discussionmentioning

confidence: 99%

Quorum quenching and anti-biofilm activities of halotolerant Bacillus strains isolated in different environments in Algeria

Aichar

Muras

Parga

et al. 2022

Journal of Applied Microbiology

View full text Add to dashboard Cite

show abstract

“…Societies also need significant resources and dedicated funding to deal with emerging and re-emerging infectious diseases focusing on its future recurring possibilities, prevention and management [ 157 ]. There should be incentives given to people for early reporting [ 158 ] followed by developing strategies to prevent antimicrobial resistance [ 159 , 160 ].…”

Section: Discussionmentioning

confidence: 99%

Multistakeholder Participation in Disaster Management—The Case of the COVID-19 Pandemic

et al. 2021

View full text Add to dashboard Cite

The coronavirus disease 2019 (COVID-19) pandemic is affecting society’s health, economy, environment and development. COVID-19 has claimed many lives across the globe and severely impacted the livelihood of a considerable section of the world’s population. We are still in the process of finding optimal and effective solutions to control the pandemic and minimise its negative impacts. In the process of developing effective strategies to combat COVID-19, different countries have adapted diverse policies, strategies and activities and yet there are no universal or comprehensive solutions to the problem. In this context, this paper brings out a conceptual model of multistakeholder participation governance as an effective model to fight against COVID-19. Accordingly, the current study conducted a scientific review by examining multi-stakeholder disaster response strategies, particularly in relation to COVID-19. The study then presents a conceptual framework for multistakeholder participation governance as one of the effective models to fight against COVID-19. Subsequently, the article offers strategies for rebuilding the economy and healthcare system through multi-stakeholder participation, and gives policy directions/decisions based on evidence to save lives and protect livelihoods. The current study also provides evidence about multidimensional approaches and multi-diplomatic mechanisms during the COVID-19 crisis, in order to examine dimensions of multi-stakeholder participation in disaster management and to document innovative, collaborative strategic directions across the globe. The current research findings highlight the need for global collaboration by working together to put an end to this pandemic situation through the application of a Multi-Stakeholder Spatial Decision Support System (MS-SDSS).

show abstract

“…For instance, Rawson et al (2020) found that 72% of COVID-19 patients received antibiotics during hospital admission, while less than 10% experienced bacterial/fungal coinfections. Thus, some studies warn that a marked increase in antibiotic-resistant bacteria should be expected (Miranda et al, 2020) and this will cause millions of human deaths annually by 2050 (Kost, 2021).…”

Section: Impacts Of Cecs On Ecosystems and Human Healthmentioning

confidence: 99%

Contaminants of Emerging Concern: A Review of Biological and Economic Principles to Guide Water Management Policies

Xabadia

Esteban

Martínez

et al. 2021

IRERE

View full text Add to dashboard Cite

Awareness regarding water contamination has increased recently due to the emergence of a multitude of pollutants that pose a high risk to ecosystems and human health. The huge number and heterogeneity of contaminants of emerging concerns (CECs), in terms of their occurrence, biochemical behavior, and environmental impacts complicate their monitoring and control. This paper reviews empirical literature on the current situation of CECs to analyze how the identification and control of these emissions have been addressed. The results highlight the need for the risks and impacts of these emerging contaminants to be assessed from an integrated perspective, and for accurate estimates of the cost-efficiency of abatement technologies, taking into account potential side effects, to be provided. Thus, there

show abstract

Geospatial Spread of Antimicrobial Resistance, Bacterial and Fungal Threats to Coronavirus Infectious Disease 2019 (COVID-19) Survival, and Point-of-Care Solutions

Cited by 14 publications

References 138 publications

Quorum quenching and anti-biofilm activities of halotolerant Bacillus strains isolated in different environments in Algeria

Quorum quenching and anti-biofilm activities of halotolerant Bacillus strains isolated in different environments in Algeria

Multistakeholder Participation in Disaster Management—The Case of the COVID-19 Pandemic

Contaminants of Emerging Concern: A Review of Biological and Economic Principles to Guide Water Management Policies

Contact Info

Product

Resources

About