Geometric algorithms for containment analysis of rotational parts

Karnik, Mukul; Gupta, Satyandra K.; Magrab, Edward B.

doi:10.1016/j.cad.2004.06.007

Cited by 16 publications

(9 citation statements)

References 9 publications

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“…Feature interactions and multiple interpretations still pose significant challenges to successful extraction of features [Car04,Car06]. Some of these techniques appear to be promising for specific domains such as manufacturing cost estimation, while some others can be used as a filter to quickly prune dissimilar objects based on the shape similarity assessment criteria [Gup99,Kar05,Ram01].…”

Section: Literature Surveymentioning

confidence: 99%

Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP

Cardone¹,

Sriram²,

Albers³

et al. 2009

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A high-affinity inhibitor protein called CIP , which can be produced by small truncations of p35, was earlier identified by Amin, Albers, and Pant. P35 is one of the physiological activators of cdk5, a member of the cyclin-dependent kinase family. P25 is an activator derived from the truncation of the physiological cdk5 activator p35 upon exposure to Aβ peptides, and it is known to be associated with the hyperphosphorylation of specific neuronal proteins. This typically occurs in the case of neurodegenerative diseases such as Alzheimer's. In this paper we study in silico the binding mechanism of cdk5-p25 and cdk5-CIP complexes more in detail. This provides a better understanding of the inhibitory activity of the protein CIP. We use a geometry-based technique to verify the following hypothesis: p25's truncation provides increased flexibility to CIP, and hence CIP is able to conform better to cdk5 interface than p25. Therefore CIP is expected to bind to cdk5 more easily than p25 and prevent it from reaching its active conformation. Our in silico study is based on a geometry-based alignment algorithm. The algorithm is capable of efficiently aligning two protein conformations with respect to their interfaces, which are represented as point sets. The algorithm is based on biochemical criteria as well as geometrical ones. Our results indicate the validity of the flexibility hypothesis. They could be used, along with some observations we made on cdk5 activation, as a basis for a set of very targeted and therefore more efficient molecular dynamics simulations.

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Section: Literature Surveymentioning

confidence: 99%

Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP

Cardone¹,

Sriram²,

Albers³

et al. 2009

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“…Many different types of approaches have been developed [8], [3][4], [14], [23]. Feature based techniques appear to be promising for domains such as machined parts.…”

Section: Part Search Techniques 31 Search Based On a Query Partmentioning

confidence: 99%

Content-Based Search Techniques for Searching CAD Databases

Gupta

Cardone

Deshmukh

2006

Computer-Aided Design and Applications

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The popularity of 3D CAD systems is resulting in large assembly and part databases being created by product development organizations. Over the last few years several content-based techniques have emerged to search these databases. Ability to perform content-based searches on CAD databases is expected to help the designers and manufacturing engineers in many different ways. Representative examples include part-family formation, redesign suggestion generation, supplier selection, cost estimation, tooling design, machine selection, stock selection, and design reuse. This paper covers the following three topics. First, it presents an overview of different types of part search techniques. Second, it presents an overview of the different aspects of assembly search techniques. Finally, it identifies the open challenges in these areas and outlines future research directions.

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“…We have presented a survey in [2]. Representative techniques include shape histogram-based techniques [9,13,18,21], graph-based techniques [1,10,19], spatial function based techniques [5,6,11,16,17], feature-based techniques [2,3,8,14,22]. The features can be represented as points or vectors in n dimension space where each dimension represents some significant characteristic of the feature.…”

mentioning

confidence: 99%

Similarity Assessment Based on Face Alignment Using Attributed Vectors

Cardone¹,

Gupta²

2006

Computer-Aided Design and Applications

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In certain shape similarity assessment applications, type, locations, and orientations of faces in boundary representations plays a key role in determining similarity between two parts. This paper describes an algorithm that assesses similarity between two parts by explicitly aligning their faces and hence accounts for these face attributes. The approach involves extracting attributed applied vectors from the face information of parts and aligning the two sets of attributed applied vectors using rigid body transformations. The algorithm uses a customizable distance function to align attributed applied vectors. The distance between two aligned attributed applied vector sets is used as a measure of similarity between two parts. This paper also presents computational results to illustrate discrimination capability of the algorithm.Keywords: Shape similarity assessment, alignment of models, and design reuse. INTRODUCTIONOver the last fifteen years 3D CAD systems have become very popular in the industry. These CAD systems are being used to generate 3D models of parts. Nowadays, organizations routinely set up databases of CAD models to enable all participants in the product development process to have access to 3D data to support their functions. CAD databases for even moderate size companies are expected to be large in size. Intuitively, if two products are similar, it is possible to reuse information about one product to derive corresponding information about the other one. There are many possible applications where reuse of information can be of significant value. Representative examples include part-family formation, redesign suggestion generation, supplier selection, cost estimation, tooling design, machine selection, stock selection, and design reuse. The ability to search for similar products in a database by specifying a query product is expected to help companies in significantly reducing the associated time and cost compared with the manual methods of locating the similar products. In [12] an overview on contentbased search techniques for parts and assemblies is given. In certain applications, locations, type, and orientations of faces play a major role in determining similarity between two parts. For example, similarity between two molded parts from the tool maker selection point of view needs to be assessed by analyzing characteristics of part faces. For example, face parameters such as spatial location, type and curvature distribution determine the type and complexity of the tooling needed to manufacture the part. Similarly, the face area determines the size of the tooling. Face features do not always have explicitly defined parameters. Hence we need to identify components of face feature vectors that are significant in determining the similarity between two parts from the tooling point of view. Shape similarity assessment problem has been studied extensively in literature. We have presented a survey in [2]. Representative techniques include shape histogram-based techniques [9,13,18,21], graph-bas...

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Geometric algorithms for containment analysis of rotational parts

Cited by 16 publications

References 9 publications

Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP

Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP

Content-Based Search Techniques for Searching CAD Databases

Similarity Assessment Based on Face Alignment Using Attributed Vectors

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