Arch Pediatr Adolesc Med
 1978
DOI: 10.1001/archpedi.1978.02120290093019
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Gentamicin-Resistant Klebsiella Infections in a Neonatal Intensive Care Unit

Arthur I. Eidelman1
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Cited by 14 publications

(13 citation statements)
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“…The occurrence of drug-resistant Klebsiella pneumoniae as a cause of life-threatening disease in intensive care nurseries (1,10,16,17,23) remains a challenge in the management of this type ofselected patient population. Despite antibiotic therapy, drug-resistant K. pneumoniae strains can colonize the intestines and nasopharynx (2,8,24,26) and invade tissues and blood, causing lethal or potentially lethal infections (13,17,21,25). We report here the characteristics of nine strains of K. pneumoniae isolated from an outbreak ofinfection and compare the properties of these strains with those of other strains previously studied (23) in connection with neonatal infections.…”
mentioning
confidence: 93%
“…Despite antibiotic therapy, drug-resistant K. pneumoniae strains can colonize the intestines and nasopharynx (2, 8,24,26) and invade tissues and blood, causing lethal or potentially lethal infections (13,17,21,25). We report here the characteristics of nine strains of K. pneumoniae isolated from an outbreak ofinfection and compare the properties of these strains with those of other strains previously studied (23) Antibiotic susceptibility testing and transfer ofresistance.…”
mentioning
confidence: 97%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The occurrence of drug-resistant Klebsiella pneumoniae as a cause of life-threatening disease in intensive care nurseries (1,10,16,17,23) remains a challenge in the management of this type ofselected patient population. Despite antibiotic therapy, drug-resistant K. pneumoniae strains can colonize the intestines and nasopharynx (2,8,24,26) and invade tissues and blood, causing lethal or potentially lethal infections (13,17,21,25). We report here the characteristics of nine strains of K. pneumoniae isolated from an outbreak ofinfection and compare the properties of these strains with those of other strains previously studied (23) in connection with neonatal infections.…”
mentioning
confidence: 93%
“…Despite antibiotic therapy, drug-resistant K. pneumoniae strains can colonize the intestines and nasopharynx (2, 8,24,26) and invade tissues and blood, causing lethal or potentially lethal infections (13,17,21,25). We report here the characteristics of nine strains of K. pneumoniae isolated from an outbreak ofinfection and compare the properties of these strains with those of other strains previously studied (23) Antibiotic susceptibility testing and transfer ofresistance.…”
mentioning
confidence: 97%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…13 Increased utilization of long-term indwelling catheters and other invasive procedures and the administration of parenteral alimentation were followed by the growing prevalence of nosocomial infections caused by coagulase-negative staphylococci. 1 ' 2,4,5 Given the wide range of possible etiologic agents, treatment protocols of neonatal sepsis were aimed at providing a broad-spectrum coverage, the most common combination being a penicillin derivative and an aminoglycoside agent. 6 " 9 The extensive use of antibiotics has resulted in the emergence of resistant bacterial strains such as gentamicin-resistant Klebsiella species, third-generation cephalosporin-resistant gram-negative organisms, and methicillin-resistant staphylococci.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Infants in intensive care nurseries are susceptible to Klebsiella pneumoniae infections that often progress from respiratory or intestinal colonization to septicemia and meningitis (2,4,5). Klebsiella strains causing such infections generally are plasmid-bearing strains resistant to antibiotics used previously in the nursery, including aminoglycosides and beta-lactams.…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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