2004
DOI: 10.3122/jabfm.17.2.108
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Genital Dysplasia in Women Infected with Human Immunodeficiency Virus

Abstract: 0003). A lower CD4؉ count nadir was strongly associated with genital dysplasia (P ‫؍‬ .0003).Conclusion: A history of greater immunosuppression, as measured by the nadir of a patient's CD4

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Cited by 13 publications
(13 citation statements)
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“…In addition, infiltrating lymphocytes are correlated with regression of genital warts in both humans and animal models (28 -31). In the setting of HIV infection, peripheral CD4 counts are inversely correlated with the presence of CIN, indicating a protective role of CD4ϩ T cells in this population (32). Because our study is a cross-sectional study, the functional role of the lymphocytic infiltrates in CIN lesions cannot be ascertained.…”
Section: Hiv Infection Results Inmentioning
confidence: 62%
“…In addition, infiltrating lymphocytes are correlated with regression of genital warts in both humans and animal models (28 -31). In the setting of HIV infection, peripheral CD4 counts are inversely correlated with the presence of CIN, indicating a protective role of CD4ϩ T cells in this population (32). Because our study is a cross-sectional study, the functional role of the lymphocytic infiltrates in CIN lesions cannot be ascertained.…”
Section: Hiv Infection Results Inmentioning
confidence: 62%
“…26 Although HIV viral load in our study was not predictive of CIN, the association of CIN with higher HIV viral load warrants further investigation.…”
Section: Discussionmentioning
confidence: 90%
“…Th e prevalence of cervical dysplasia was 3.9-fold higher among HIV-infected women than among women not infected with HIV (Duerr et al 2001). Before highly active antiretroviral therapy (HAART) became the standard of care for patients infected with HIV, the risk of cervical dysplasia increased progressively as immune function declined; as measured by the fall in CD4 ϩ cells (Taylor et al 2004).…”
Section: Discussionmentioning
confidence: 99%