Genetics of Epidermodysplasia Verruciformis

Kawase, Masaaki

doi:10.5772/55340

Cited by 3 publications

(7 citation statements)

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“…Sun protection was recommended to reduce the risk of developing skin cancer, but, unfortunately, proved difficult, as the patients were farmers with no alternative livelihood. Patients with EV, especially HPV-5/-8, are prone to developing non-melanoma skin cancers, particularly squamous cell carcinomas ( 3 , 4 ); therefore, they require closer attention and follow-up.…”

Section: Discussionmentioning

confidence: 99%

Epidermodysplasia Verruciformis in Fitzpatrick Skin Type VI: New Dermoscopic Findings

Yotsu,

Murase,

Fukaura

et al. 2023

Acta Derm Venereol

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Section: Discussionmentioning

confidence: 99%

Epidermodysplasia Verruciformis in Fitzpatrick Skin Type VI: New Dermoscopic Findings

Yotsu,

Murase,

Fukaura

et al. 2023

Acta Derm Venereol

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“…The lesions can progress into keratinocyte‐derived skin cancers, especially in sun/ultraviolet‐exposed areas 15,16 . The most common genetic alterations in patients with EV are loss‐of‐function mutations in genes EVER1/TMC6 and EVER2/TMC8 (17q25.3) 1 . These genes, normally, confer immunity against chronic and persistent HPV infections by the beta genus 17 .…”

Section: Discussionmentioning

confidence: 99%

“…15,16 The most common genetic alterations in patients with EV are loss-of-function mutations in genes EVER1/TMC6 and EVER2/TMC8 (17q25.3). 1 These genes, normally, confer immunity against chronic and persistent HPV infections by the beta genus. 17 The gene product interacts with the zinc-transporter-1 (ZnT-1), maintaining the cellular zinc homeostasis and preventing replication of beta HPV.…”

Section: Discussionmentioning

confidence: 99%

“…Epidermodysplasia verruciformis (EV) is a rare inherited or acquired genodermatosis caused by increased susceptibility to infection by beta subtypes of human papillomavirus (HPV). Most patients (up to 75%) 1 with inherited EV have loss-of-function mutations in EVER1/ TMC6 or EVER2/TMC8 genes, [2][3][4] the protein products of which maintain immunity against the virus. These individuals are at an increased risk for developing virally driven squamous cell carcinoma of the skin.…”

Section: Introductionmentioning

confidence: 99%

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Cervical dysplasia in a patient with inherited epidermodysplasia verruciformis—A mere coincidence?

2020

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Epidermodysplasia verruciformis (EV) is a rare inherited or acquired genodermatosis caused by increased susceptibility to infection by the beta subtypes of human papillomavirus (HPV). The co‐occurrence of EV with high‐risk (HR) HPV infection leading to cervical dysplasia is unreported in the literature to date. We report a patient with inherited EV who developed extensive anogenital and cervical dysplasia linked to concurrent HR‐HPV infection. Literature review suggests that there is a negative correlation of cervical dysplasia and cervical cancer with EV, which suggests that this patient's presentation and course are exceptional.

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“…(2) Jiménez-Penago, 2021;Karalija, 2020;Kawase, 2013;Khan, 2018;Khan, 2019;La Pergola, 2017;Licata, 2015;Mancini, 2014;Mechergui, 2016;Morshedloo, 2017;Moukhfi, 2022;Napoli, 2020;Özer et al, 2018;Popa, 2021;Sharififard,, 2018;Simirgiotis, 2020;Stanojevic, 2016;Tanasescu, 2019;Teixeira, 2013;Tsoumani, 2022;Tuttolomondo, 2016;Yilar, 2013;Zinno, 2023] Yilar, 2013…”

Section: Rosmarinus Officinalisunclassified

Extraction of essential oils by hydrodistillation of four aromatic species: Conditioning, extraction conditions, yield and chemical composition

Olascuaga-Castillo,

Castillo-Medina,

Villacorta-Zavaleta

et al. 2024

Sci. agropecu.

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Essential oils are one of the most important products in the agricultural and food industry, as they are obtained from aromatic plants using various extraction techniques, such as steam distillation or hydrodistillation. However, these methods present challenges, such as low efficiency, limited selectivity, extensive use of solvents and long extraction times. Moreover, the quality of the oils obtained can be affected by hydrolysis or oxidation due to the duration and amount of water used in the process. This review updates the information on Clevenger-type hydrodistillation extraction of four high-value commercial plant species: Matricaria chamomilla, Rosmarinus officinalis, Origanum vulgare, and Eucalyptus spp. The aim is to evaluate the results of original articles, considering the origin and characteristics of the plant material, extraction conditions, yield and metabolites. The search covered a 10-year period (2013-2023) in Scopus, Web of Science, PubMed, and Google Scholar, using keywords such as species names and terms “essential oils” and “hydrodistillation”, with Boolean connectors such as OR, AND or NOT. The results show that quality and yield are influenced by factors such as geographical regions of origin, plant part used, drying techniques or extraction conditions (plant material/water ratio, extraction temperature, extraction time, etc.). In future research, the conditions associated with the plant material and the extraction process need to be optimized in obtaining high quality essential oils.

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Genetics of Epidermodysplasia Verruciformis

Cited by 3 publications

References 68 publications

Epidermodysplasia Verruciformis in Fitzpatrick Skin Type VI: New Dermoscopic Findings

Epidermodysplasia Verruciformis in Fitzpatrick Skin Type VI: New Dermoscopic Findings

Cervical dysplasia in a patient with inherited epidermodysplasia verruciformis—A mere coincidence?

Extraction of essential oils by hydrodistillation of four aromatic species: Conditioning, extraction conditions, yield and chemical composition

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