Abstract:Studies on human genetic variations are a useful source of knowledge about human
immunodeficiency virus (HIV)-1 infection. The Langerin protein, found at the surface
of Langerhans cells, has an important protective role in HIV-1 infection. Differences
in Langerin function due to host genetic factors could influence susceptibility to
HIV-1 infection. To verify the frequency of mutations in the
Langerin gene, 118 samples from HIV-1-infected women and 99
samples from HIV-1-uninfected individuals were selected for… Show more
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