Genetic analysis for semen traits in a crossing program of Saudi Aradi with Damascus goats

Mohammed, K. M.; Khalil, M. H.; Al-Saef, A. M.

doi:10.1016/j.smallrumres.2012.10.001

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…The number of inseminating doses generated from each ejaculate depends on the volume, sperm concentration, and motile sperm after freezing/thawing. Also, techniques of semen preservation (fresh, refrigerated and frozen) and insemination (vaginal, cervical and intrauterine) are considered as very important techniques in genetic improvement programs [ 5 ]. Semen quantity and quality is commonly described by means of a wide domain of traits, including qualitative traits of the ejaculate, characteristics associated with the biochemical composition of the ejaculate, qualitative characteristics of the spermatozoa and characteristics of the inseminating dose [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Semen Characteristics of Purebred and Crossbred Male Rabbits

Abdel-Hamid

2015

PLoS ONE

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The aim of this investigation was to evaluate the semen quality traits of purebred male rabbits and their crosses under subtropical Egyptian conditions. A full 3 x 3 diallel crossing was performed for producing the first generation progeny of New Zealand White (N), Flander (F) and Rex (R) breeds. The highest ejaculate volume (p< 0.05) and percentage of live sperms (p<0.01) with the lowest percentage of sperm cell morphological abnormalities (p<0.05) had been recorded in the NF bucks. Moreover, they possessed positive estimates of direct heterosis for ejaculate volume, mass motility (Mm), individual motility (Im) and sperm cell concentration (SCC). On the contrary, pH had negative estimates of direct heterosis in all crosses and their reciprocal. Semen pH was negatively correlated with SCC (r = -0.18), Mm (r = -0.13) and Im (r = -0.23). In conclusion, the superiority of crossbreeding was particularly obvious in the New Zealand White x Flander males, which cumulated heterosis and favorable maternal effects of the Flander dams.

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Section: Introductionmentioning

confidence: 99%

Semen Characteristics of Purebred and Crossbred Male Rabbits

Abdel-Hamid

2015

PLoS ONE

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“…Few association studies have been conducted on semen production traits in goats. For example, Nickbin et al [12] investigated the HSP70 gene in Boer goats and Mohammed et al [13] calculated genetic parameters for the Damascus breed. However, the association of semen production traits to regions of the genome has yet to be investigated in Alpine and Saanen breeds despite their economic importance in the French dairy industry.…”

Section: Introductionmentioning

confidence: 99%

Genome wide association analysis on semen volume and milk yield using different strategies of imputation to whole genome sequence in French dairy goats

et al. 2020

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Background: Goats were domesticated 10,500 years ago to supply humans with useful resources. Since then, specialized breeds that are adapted to their local environment have been developed and display specific genetic profiles. The VarGoats project is a 1000 genomes resequencing program designed to cover the genetic diversity of the Capra genus. In this study, our main objective was to assess the use of sequence data to detect genomic regions associated with traits of interest in French Alpine and Saanen breeds. Results: Direct imputation from the GoatSNP50 BeadChip genotypes to sequence level was investigated in these breeds using FImpute and different reference panels: within-breed, all Capra hircus sequenced individuals, European goats and French mainland goats. The best results were obtained with the French goat panel with allele and genotype concordance rates reaching 0.86 and 0.75 in the Alpine and 0.86 and 0.73 in the Saanen breed respectively. Mean correlations tended to be low in both breeds due to the high proportion of variants with low frequencies.For association analysis, imputation was performed using FImpute for 1129 French Alpine and Saanen males using within-breed and French panels on 23,338,436 filtered variants. The association results of both imputation scenarios were then compared. In Saanen goats, a large region on chromosome 19 was significantly linked to semen volume and milk yield in both scenarios. Significant variants for milk yield were annotated for 91 genes on chromosome 19 in Saanen goats. For semen volume, the annotated genes include YBOX2 which is related to azoospermia or oligospermia in other species. New signals for milk yield were detected on chromosome 2 in Alpine goats and on chromosome 5 in Saanen goats when using a multi-breed panel. Conclusion: Even with very small reference populations, an acceptable imputation quality can be achieved in French dairy goats. GWAS on imputed sequences confirmed the existence of QTLs and identified new regions of interest in dairy goats. Adding identified candidates to a genotyping array and sequencing more individuals might corroborate the involvement of identified regions while removing potential imputation errors.

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