Generalized staphylococcal scalded skin syndrome in an anephric boy undergoing hemodialysis

A Generalized Staphylococcal Scalded Skin‐Like Disease in Lambs

“…The most characteristic cutaneous lesion and renal failure described in these lambs correlate with the disorders described previously, associated with the same syndrome in human beings and animals (WILEY et al, 1974;FRITSCH et al, 1976;ELIAS et al, 1977;LOVE and DAVIS, 1980;BORCHERS et al, 1984;CARPENTER et al, 1988).…”

“…Generalized staphylococcal scalded-skin syndrome is characterized by widespread epidermolysis, mediated by a toxin produced by S. aureus (BORCHERS et al, 1984). The dramatic cutaneous picture-exfoliation of the upper layer of the epidermis (Fig.…”

“…Generalized staphylococcal scalded-skin syndrome is an epidermolytic disease that affects humans (ELIAS et al, 1977;BORCHERS et al, 1984) and dogs (LOVE and DAVIS, 1980;CARPENTER et al, 1988). In mice the disease was experimentally induced (WILEY et al, 1974;FRITISCH et al, 1976).…”

“…In mice the disease was experimentally induced (WILEY et al, 1974;FRITISCH et al, 1976). Experimental data from animal studies have demonstrated that both immunosuppression and renal insufficiency may play a role in the pathogenesis of the disease (WILEY et al, 1974;FRITSCH et al,1976;BORCHERS et al, 1984), which is caused by the exotoxin produced by certain strains of Staphylococcus aureus (BORCHERS et al, 1984;DEMIS, 1991), which have the capacity to induce intra-epidermal separation (MELISH et al, 1972). The toxin responsible for the exfoliative phenomenon was described by MELISH et al (1972).…”

Toxic Epidermal Necrolysis Due to Antieptic Therapy in an 8‐year‐old Boy

“…SSSS mainly afflicts infants and children, rarely adults (9). Immunosuppression and renal immaturity or insufficiency are predisposing factors (31)(32)(33). Clinically, scalding of the skin is present but in contrast to TEN, the mucous membranes are not involved.…”