In [2,3] the authors introduce, study and apply a new variant of the Eggenberger-Pólya urn, called the "Rescaled" Pólya urn, which, for a suitable choice of the model parameters, is characterized by the following features: (i) a "local" reinforcement, i.e. a reinforcement mechanism mainly based on the last observations, (ii) a random persistent fluctuation of the predictive mean, and (iii) a long-term almost sure convergence of the empirical mean to a deterministic limit, together with a chi-squared goodness of fit result for the limit probabilities. In this work, motivated by some empirical evidences in [3], we show that the multidimensional Wright-Fisher diffusion with mutation can be obtained as a suitable limit of the predictive means associated to a family of rescaled Pólya urns.