General Symptomatology and Differential Diagnosis of Disseminated Sclerosis

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

“…In the years following the end of the First World War, greater attention to cognitive impairments in MS seemed to emerge: Jeliffe [ 45 ] identified frequent difficulties in formulating thought, attentional processes, and memory; Sachs and Friedman [ 46 ] established, using a statistical approach, that 15.6% of a sample of 141 cases had mental changes. As highlighted by Butler et al [ 35 ], the vagueness of the term “mental changes”, together with other limitations, did not allow for any generalizations.…”

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

“…In the years following the end of the First World War, greater attention to cognitive impairments in MS seemed to emerge: Jeliffe [ 45 ] identified frequent difficulties in formulating thought, attentional processes, and memory; Sachs and Friedman [ 46 ] established, using a statistical approach, that 15.6% of a sample of 141 cases had mental changes. As highlighted by Butler et al [ 35 ], the vagueness of the term “mental changes”, together with other limitations, did not allow for any generalizations.…”

How the Conflict between American Psychiatry and Neurology Delayed the Appreciation of Cognitive Dysfunction in Multiple Sclerosis

“…In 1922, Sachs and Friedman conducted the first English language study to attempt to formally quantify mental change in MS and delivered an address on the general symptomatology and differential diagnosis of disseminated sclerosis (the British term for MS) at the Meeting of the Association for Research in Nervous and Mental Diseases in New York. Employing systematic empirical investigation of group data, rather than customary case study data, informed by statistics, they investigated the cognitive symptoms in MS. From a clinical review of a large sample of MS patients, they reported mental changes in 15.6% of 141 cases (Sachs and Friedman 1922) and concluded that mental symptoms were prevalent in MS. However, generalizability was limited because the definition of mental changes was unspecified, patient selection was ambiguous, and researchers were dependent on I.Q.…”

Multiple sclerosis: correlation of psychiatric admissions to onset of initial symptoms

“…Reports of their frequency vary. Epidemiological principles, diagnostic and classification procedures differ and, thus, the reported frequency ranges from 15.6 to 94% (1)(2)(3)(4)(5).…”

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

“…In the years following the end of the First World War, greater attention to cognitive impairments in MS seemed to emerge: Jeliffe [ 45 ] identified frequent difficulties in formulating thought, attentional processes, and memory; Sachs and Friedman [ 46 ] established, using a statistical approach, that 15.6% of a sample of 141 cases had mental changes. As highlighted by Butler et al [ 35 ], the vagueness of the term “mental changes”, together with other limitations, did not allow for any generalizations.…”

How the Conflict between American Psychiatry and Neurology Delayed the Appreciation of Cognitive Dysfunction in Multiple Sclerosis

“…In 1922, Sachs and Friedman conducted the first English language study to attempt to formally quantify mental change in MS and delivered an address on the general symptomatology and differential diagnosis of disseminated sclerosis (the British term for MS) at the Meeting of the Association for Research in Nervous and Mental Diseases in New York. Employing systematic empirical investigation of group data, rather than customary case study data, informed by statistics, they investigated the cognitive symptoms in MS. From a clinical review of a large sample of MS patients, they reported mental changes in 15.6% of 141 cases (Sachs and Friedman 1922) and concluded that mental symptoms were prevalent in MS. However, generalizability was limited because the definition of mental changes was unspecified, patient selection was ambiguous, and researchers were dependent on I.Q.…”

Multiple sclerosis: correlation of psychiatric admissions to onset of initial symptoms

“…Reports of their frequency vary. Epidemiological principles, diagnostic and classification procedures differ and, thus, the reported frequency ranges from 15.6 to 94% (1)(2)(3)(4)(5).…”

Focus or Neglect on Cognitive Impairment Following the History of Multiple Sclerosis

“…In the years following the end of the First World War, greater attention to cognitive impairments in MS seemed to emerge: Jeliffe [ 45 ] identified frequent difficulties in formulating thought, attentional processes, and memory; Sachs and Friedman [ 46 ] established, using a statistical approach, that 15.6% of a sample of 141 cases had mental changes. As highlighted by Butler et al [ 35 ], the vagueness of the term “mental changes”, together with other limitations, did not allow for any generalizations.…”

How the Conflict between American Psychiatry and Neurology Delayed the Appreciation of Cognitive Dysfunction in Multiple Sclerosis

“…In 1922, Sachs and Friedman conducted the first English language study to attempt to formally quantify mental change in MS and delivered an address on the general symptomatology and differential diagnosis of disseminated sclerosis (the British term for MS) at the Meeting of the Association for Research in Nervous and Mental Diseases in New York. Employing systematic empirical investigation of group data, rather than customary case study data, informed by statistics, they investigated the cognitive symptoms in MS. From a clinical review of a large sample of MS patients, they reported mental changes in 15.6% of 141 cases (Sachs and Friedman 1922) and concluded that mental symptoms were prevalent in MS. However, generalizability was limited because the definition of mental changes was unspecified, patient selection was ambiguous, and researchers were dependent on I.Q.…”

Multiple sclerosis: correlation of psychiatric admissions to onset of initial symptoms

“…Reports of their frequency vary. Epidemiological principles, diagnostic and classification procedures differ and, thus, the reported frequency ranges from 15.6 to 94% (1)(2)(3)(4)(5).…”