Gender Differences in the Clinical Characteristics and Atrioventricular Nodal Conduction Properties in Patients With Atrioventricular Nodal Reentrant Tachycardia

Suenari, Kazuyoshi; Hu, Yu‐Feng; Tsao, Hsuan‐Ming; Tai, Ching‐Tai; Chiang, Chern‐En; Lin, Yenn‐Jiang; Chang, Shih‐Lin; Liu, Shin-Huei; Tuan, Ta‐Chuan; Lee, Pi-Chang; Tung, Nguyen Hưu; Huang, Sheng‐Chieh; Wu, Tsu‐Juey; Chen, Shih‐Ann

doi:10.1111/j.1540-8167.2010.01779.x

Cited by 38 publications

(48 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…105 Supporting this hypothesis is the higher incidence of SVT during the luteal phase, when progesterone levels are high. 105 Supporting this hypothesis is the higher incidence of SVT during the luteal phase, when progesterone levels are high.…”

Section: Atrioventricular Nodal Re-entry Tachycardiamentioning

confidence: 96%

See 1 more Smart Citation

Effect of Female Sex on Cardiac Arrhythmias

Gowd

Thompson

2012

Cardiology in Review

View full text Add to dashboard Cite

We performed a systematic literature review to examine the effect of female sex on cardiac electrophysiology and arrhythmias. Women have faster resting heart rates yet longer QTc intervals. Women also have shorter PR and QRS intervals; these are presumed to be due to the small heart size of women and hormonal effects on ion channels. Women are two times more likely to experience atrioventricular nodal re-entry tachycardia than men. In contrast to atrioventricular nodal re-entry tachycardia, accessory-pathway-mediated atrial arrhythmias are less common in women, and women have more concealed and fewer manifest accessory pathways. Supraventricular tachycardia in women varies with the menstrual cycle and is more frequent in the luteal phase and inversely correlated with estrogen levels. Atrial fibrillation (AF) is less prevalent in women, but the absolute number of women with AF is higher because AF prevalence increases with age and women live longer. Also, complications of AF are greater in women. Women are generally less prone to ventricular arrhythmias, but they comprise a higher percentage of symptomatic subjects with congenital long QT syndrome and are more often affected by drugs that prolong the QT. Women are less prone to arrhythmias during pregnancy although they commonly complain of palpitations, which are sometimes related to the increase in heart rate during pregnancy. Clinicians should explore the relationship of arrhythmias to the menstrual cycle in female patients and should know that the menstrual cycle may affect the induction of arrhythmias during electrophysiological testing. Clinicians should also be aware that the arrhythmia and the result of clinical trials examining arrhythmia treatment may have different implications in women than in men.

show abstract

Section: Atrioventricular Nodal Re-entry Tachycardiamentioning

confidence: 96%

“…102,105,147 The resting heart rate in postmenopausal women remains higher than men. 102,105,147 The resting heart rate in postmenopausal women remains higher than men.…”

Section: Effect Of Menopausementioning

confidence: 99%

Effect of Female Sex on Cardiac Arrhythmias

Gowd

Thompson

2012

Cardiology in Review

View full text Add to dashboard Cite

show abstract

“…Women have longer QT intervals (even when corrected for heart rate), ventricular action potential durations, and ventricular refractory periods in comparison with men. [1][2][3][4] Sex hormones account for most of the differences in the cardiac electrophysiological properties observed between females and males. Much of these data have been derived from experimental studies in a variety of animal models and some limited human data.…”

Section: Sex Differences In Cardiac Electrophysiologymentioning

confidence: 99%

“…Women also have shorter PR, AH, and HV intervals, shorter atrial and atrioventricular node refractory periods, and shorter QRS durations. 1,2 The QT interval shortens after puberty in males. Women have longer QT intervals (even when corrected for heart rate), ventricular action potential durations, and ventricular refractory periods in comparison with men.…”

Section: Sex Differences In Cardiac Electrophysiologymentioning

confidence: 99%

Atrial Fibrillation and Ventricular Arrhythmias

Gillis

2017

Circulation

View full text Add to dashboard Cite

ABSRACT: Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias, and sudden cardiac death are recognized. Sex hormones cause differences in cardiac electrophysiological parameters between men and women that may affect the risk for arrhythmias. The incidence and prevalence of AF is lower in women than in men. However, because women live longer and AF prevalence increases with age, the absolute number of women with AF exceeds that of men. Women with AF are more symptomatic, present with more atypical symptoms, and report worse quality of life in comparison with men. Female sex is an independent risk factor for death or stroke attributable to AF. Oral anticoagulation therapy for stroke prevention has similar efficacy for men and women, but older women treated with warfarin have a higher residual risk of stroke in comparison with men. Women with AF are less likely to receive rhythm control antiarrhythmic drug therapy, electric cardioversion, or catheter ablation in comparison with men. The incidence and prevalence of sustained ventricular arrhythmias and sudden cardiac death are lower in women than in men. Women receiving implantable cardioverter defibrillators for primary prevention of sudden cardiac death are less likely to experience sustained ventricular arrhythmias in comparison with men. In contrast, women receiving a cardiac resynchronization therapy implantable cardioverter defibrillator for the treatment of heart failure are more likely to benefit than men. Women are less likely to be referred for implantable cardioverter defibrillator therapy despite current guideline recommendations. Women are more likely to experience a significant complication related to implantable cardioverter defibrillator implantation in comparison with men. Whether sex differences in treatment decisions reflect patient preferences or treatment biases requires further study.

show abstract

“…[8][9][10][11][12] In brief, dual AV nodal pathway curves were characterized by a jump (≥50 ms) in the H1-H2 interval at a critical range of A1-A2 coupling intervals (10 ms decrements), resulting in a discontinuity between the portion of the curve to the right of the jump in the H1-H2 interval (fast pathway conduction) and the portion of the curve to the left of the jump (slow pathway conduction). A multiple anterograde AV nodal pathway physiology was defined by AV nodal conduction curves with ≥2 discontinuities.…”

Section: Definitionsmentioning

confidence: 99%

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Tseng

Tsai

et al. 2011

Circ J

Self Cite

View full text Add to dashboard Cite

Background: This study aimed to investigate the impact of aging on electrophysiological characteristics in patients with atrioventricular nodal re-entrant tachycardia (AVNRT). Methods and Results:The 2,111 patients who underwent an electrophysiological study and radiofrequency (RF) catheter ablation of AVNRT were enrolled. The patients were divided into 4 groups according to age (group 1: <20 years; group 2: 20-39 years; group 3: 40-59 years; and group 4: ≥60 years). The gender distribution differed with age. The atrio-Hisian interval, and effective refractory periods (ERP) of the right atrium, ventricle, antegrade slow pathway, retrograde slow pathway and fast pathway, and tachycardia cycle length all increased with age. However, a paradoxical change in the fast pathway ERP was noted. The fast pathway ERP was significantly longer in group 2 than in other groups, and was associated with the largest tachycardia window. The response to catecholamines was similar between different age groups. Procedure time, radiation time, and complications did not differ. However, the number of RF impulses was higher in group 2 compared with other groups (7.6±9.3, P=0.04), which might imply a differing complexity during the ablation. Conclusions:Paradoxical aging changes of AVN electrophysiological characteristics were associated with a different atrioventricular nodal conduction property and the number of RF impulses. (Circ J 2011; 75: 1581 -1584

show abstract

Gender Differences in the Clinical Characteristics and Atrioventricular Nodal Conduction Properties in Patients With Atrioventricular Nodal Reentrant Tachycardia

Abstract: Gender differences in the anterograde and retrograde AV nodal electrophysiology were noted in the patients with AVNRT.

Cited by 38 publications

References 23 publications

Effect of Female Sex on Cardiac Arrhythmias

Effect of Female Sex on Cardiac Arrhythmias

Atrial Fibrillation and Ventricular Arrhythmias

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Contact Info

Product

Resources

About