Objectives:The purpose of this study is to describe text-to-speech system for the Tigrigna language, using dialog fusion architecture and developing a prototype text-to-speech synthesizer for Tigrigna Language. Methods : The direct observation and review of articles are applied in this research paper to identify the whole strings which are represented the language. Tools used in this work are Mathlab, LPC, and python. In this paper LSTM deep learning model was applied to find out accuracy, precision, recall, and Fscore. Findings: The overall performance of the system in the word level which is evaluated by NeoSpeech tool is found to be 78% which is fruitful. When it comes to the intelligibility and naturalness of the synthesized speech in the sentence level, it is measured in MOS scale and the overall intelligibility and naturalness of the system are found to be 3.28 and 3.27 respectively. Based on the experiment LSTM Deep learning model provides an accuracy of 91.05%, the precision of 78.05%, recall of 86.59 %, and F-score of 83.05% respectively. The values of performance, intelligibility, and naturalness are inspiring and show that diphone speech units are good candidates to develop a fully functional speech synthesizer. Novelty: The researchers come up with the first text to speech LSTM deep learning model for the Tigrigna language which is critical and will be a baseline for other related research to be done for Tigrigna and other languages.