Gastric emptying time in patients with primary hypothyroidism

Kahraman, Hakkı; Kaya, N.; Demirçali, Arif Engin; Bernay, Irem; Tanyeri, F.

doi:10.1097/00042737-199709000-00014

Cited by 42 publications

(30 citation statements)

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“…Additionally, gastric dysmotility is significantly more frequent in hypothyroid patients and is a result of muscle edema and altered myoelectrical activity [57] . Despite a few contradictory results [58] , the hypothyroid state seems to delay gastric emptying [19,59] . Phytobezoar due to hypothyroidism has also been reported [60] .…”

Section: Esophagus and Stomachmentioning

confidence: 99%

Consequences of dysthyroidism on the digestive tract and viscera

Daher¹,

Yazbeck²,

Jaoude³

et al. 2009

WJG

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Thyroid hormones define basal metabolism throughout the body, particularly in the intestine and viscera. Gastrointestinal manifestations of dysthyroidism are numerous and involve all portions of the tract. Thyroid hormone action on motility has been widely studied, but more complex pathophysiologic mechanisms have been indicated by some studies although these are not fully understood. Both thyroid hormone excess and deficiency can have similar digestive manifestations, such as diarrhea, although the mechanism is different in each situation. The liver is the most affected organ in both hypo-and hyperthyroidism. Specific digestive diseases may be associated with autoimmune thyroid processes, such as Hashimoto's thyroiditis and Grave's disease. Among them, celiac sprue and primary biliary cirrhosis are the most frequent although a clear common mechanism has never been proven. Overall, thyroidrelated digestive manifestations were described decades ago but studies are still needed in order to confirm old concepts or elucidate undiscovered mechanisms. All practitioners must be aware of digestive symptoms due to dysthyroidism in order to avoid misdiagnosis of rare but potentially lethal situations.

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Section: Esophagus and Stomachmentioning

confidence: 99%

Consequences of dysthyroidism on the digestive tract and viscera

Daher¹,

Yazbeck²,

Jaoude³

et al. 2009

WJG

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“…Because the blood concentration of PegIFN a-2b increased more slowly, delayed gastric motility was considered milder during PegIFN a-2b therapy than during non-PegIFN a-2b therapy. Gastric motilityrelated factors other than interferon, diabetes mellitus and hypothyroidism are known to cause delayed gastric emptying [22,23]. However, our patients had no change in blood glucose levels or thyroid hormonal levels after Peg-IFN a-2b initiation (data not shown).…”

Section: Discussionmentioning

confidence: 57%

Effect of Mosapride Citrate on Gastric Emptying in Interferon-Induced Gastroparesis

et al. 2012

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“…15,16 57.2% of hypothyroid patients complained of fatigue in day to day activities, mostly by older patients. Many hypothyroid patients experience persistent fatigue and fatigue-related symptoms, as well as poor performance on various domains of neurocognitive functioning.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of general and cutaneous manifestations of hypothyroidism: a single center experience in Odisha

Kumar

Aslami

2016

Int J Res Dermatol

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Background: Endocrine diseases may induce manifestation through the skin. Hypothyroidism is known to cause a wide range of general and skin manifestations. Dermatologists may commonly see skin disorders that reflect an underlying hypothyroid state. The objective of the study was to evaluate varied general and cutaneous manifestations of hypothyroidism.Methods: A hospital based descriptive clinical study was conducted in the department of Dermatology, Venerology and Leprosy, MKCG Medical College, Berhampur, Odisha. Diagnosed cases of hypothyroidism were included as the study subjects. An informed consent was taken from each patient. Institutional ethics committee of the college approved the Study.Results: 320 patients of hypothyroidism were evaluated. Maximum patients 115 (35.9%) were among 31-40 years of age group. Male to female ratio was 1:5.7. The percentage of hypothyroid patients who complained of constipation, fatigue, Cold intolerance, weight gain and neck swelling was 75.0%, 57.2%, 50.9%, 35.9% and 31.9% respectively. Among females, 54.5% were having irregular menses. The most common cutaneous symptom was dry course skin (75.9%), followed by diffuse hair loss (50.9%), puffy oedema (48.1%), decreased sweating (11.9%) and yellow skin (9.1%). The most observed cutaneous sign was xerosis (66.9%), followed by alteration in skin texture (55.0%). Some patients showed more than one cutaneous signs. The most common hair changes in our patients were diffuse hair loss (55.9%), followed by course scalp hair (29.4%).Conclusions: The interaction between hypothyroidism and skin is of profound clinical importance. So, dermatologists need to be alert of the ways in which these two organ systems interact, so that early diagnosis and management of hypothyroidism may ensue.

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Gastric emptying time in patients with primary hypothyroidism

Cited by 42 publications

References 0 publications

Consequences of dysthyroidism on the digestive tract and viscera

Consequences of dysthyroidism on the digestive tract and viscera

Effect of Mosapride Citrate on Gastric Emptying in Interferon-Induced Gastroparesis

Evaluation of general and cutaneous manifestations of hypothyroidism: a single center experience in Odisha

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