Gargoylism

The Oral Changes in Gargoylism

“…Thus, in the case reported here, there was hardly any growth of the spine and skull between the ages of 3 and 6 years. The histological features of the disordered bone formation have been described by Strauss (1948), Lindsay et al (1948), Nisbet & Cupit (1954) and Dawson (1954).…”

“…Ellis et al (1936) described the teeth of two of their patients as 'massive'. In 2 cases described by Cordes & Hogan (1942) and by Lindsay et al (1948), the teeth in addition to being peg-shaped were different in size and shape from those on the opposite side of the mouth. In 9 cases the structure of the teeth was described as defective or hypoplastic.…”

Les conducteurs du gène del'atrophia gyrata chorioideae et retinaede Fuchs (anomalie d'Aider)

“…On connait par contre au moins 100 cas de maladie de Hurler, oil il n'existait pas d'anomalie d'Alder: Ullrich (1943), Boldt (1943, 1 cas), Nja (1945, 1 cas), Lahey, Lomas et Worth (1947), Lindsay, Reilly, Gotham et Skahen (1948, 3 cas), Bohlau (1949, 1 cas), Menger (1950, 1 cas), Undritz (1954. Nous avons eu l'occasion d'observer deux freres, atteints de gargoylisme; chez aucun d'entre eux il n'y avait une anomalie d'Alder.…”

Gargoylism: Report of a case

“…De Lange, Gerlings, de Kleyn, and Lettinga (1944), quoted by Lindsay, Reilly, Gotham, and Skahen (1948), and Strauss (1947) suggested that the storage material was a carbohydrate. Lindsay and his associates made an important contribution in 1948.…”

“…They suggested that the abnormal material was glycogen or glycoprotein. One hundred and seven cases were collected from the literature by Reilly and Lindsay (1948). This article discussed the biochemical aspects of the condition and described the changes in the cornea and middle and inner ears.…”