Gambaran Klinis Kriptorkismus di Poliklinik Endokrinologi Anak RS Dr. Cipto Mangunkusumo, Jakarta, Tahun 1998 - 2002

Suryawan, Wayan Bikin; Batubara, Jose Rl; Tridjaja, Bambang; Pulungan, Aman B

doi:10.14238/sp5.3.2003.111-6

Cited by 3 publications

(3 citation statements)

References 3 publications

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“…The efficacy is assessed using increase of TSH and decrease of FT4 level. Vitamin-D values were categorized as being deficient when <20 ng/L (50 nmol/L) and insufficient between 21 and 29 ng/L (52.5-72.5 nmol/L), on the basis of Endocrinology society [6].…”

Section: Methodsmentioning

confidence: 99%

Efficacy of Vitamin-D Supplement on Thyroid Profile in Children with Graves’ Disease

Pratita¹,

Arto²,

Arto³

2020

Open Access Maced J Med Sci

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BACKGROUND: Many studies have shown low Vitamin-D level as a risk factor for autoimmune diseases, especially multiple sclerosis and thyroid disease. Graves’ disease (GD) is an autoimmune disease caused by autoantibodies that stimulate thyroid-stimulating hormone (TSH) receptors by increasing thyroid hormone synthesis and secretion. Several studies report that many patients with autoimmune thyroid disease including GD have low Vitamin-D status. AIM: The objective of the study was to evaluate the effect of Vitamin-D supplement on GD patients on improvement in thyroid hormone levels. METHODS: Open random clinical trial was conducted in GD patients to determine changes in thyroid hormone to achieving normal levels between those receiving methimazole plus Vitamin-D supplementation compared with those who only received methimazole. Patients were checked for TSH receptor antibody, thyroid profile and Vitamin-D level before treatment and rechecked for thyroid profile and Vitamin-D level 3 months after treatment. t-test used to compare the drug efficacy (p < 0.05) in two groups. RESULTS: From 25 children with GD accompanied by Vitamin-D deficiency with an average value of Vitamin-D was 16 ng/mL. GD children who receive methimazole with Vitamin-D supplement had elevated TSH levels in the 3rd month of therapy that was significantly different compared to GD children who received methimazole only (p = 0.00), and the increase of TSH was also followed by an increase in Vitamin-D levels. CONCLUSION: All children with GD had Vitamin D deficiency, and the addition of Vitamin-D supplement to GD therapy would improve TSH faster than children who did not receive Vitamin-D supplement.

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Section: Methodsmentioning

confidence: 99%

Efficacy of Vitamin-D Supplement on Thyroid Profile in Children with Graves’ Disease

Pratita¹,

Arto²,

Arto³

2020

Open Access Maced J Med Sci

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“…Modalitas terapi utama untuk penanganan ectopic testis adalah dengan pembedahan pada umur 6-12 bulan, sesuai dengan konsensus penanganan undesensus maupun ectopic testis negara-negara Nordik Ritzen et al (2007). Tidak ada terapi hormonal untuk menurunkan testis, jika testis tidak menurun secara spontan pada usia enam bulan, maka dilakukan tindakan operasi sebelum usia 12 bulan, begitu pula jika diagnosis baru bisa ditegakkan setelah usia enam bulan, maka tindakan operasi harus segera dilakukan Suryawan et al (2017).…”

Section: Gambar 2 Penampakan Testis Kanan Ketika Operasiunclassified

Perineal Ectopic Testis in One and A Half Year Old Child As A Rare Congenital Anomaly: A Case Report

Surya¹,

Faadilah

Sriyono

2023

medicra

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Ectopic testis is described as an abnormality of testicle development in which one or both testicles aren’t descending through the testicle normal pathways. Among all newborns with undescended testis, only 1% are diagnosed as ectopic testis. In this case, an 18 months old boy was presented to hospital with chief complaint of impalpable testis dextra. Phsical examination showed the right testis was not palpable in the scrotum and perineum. Ultrasonography examination showed a right testis in the perineum with normal volume and vascularization. Right orchidopexy was performed to correct the location of the testis. Early diagnostic of ectopic testis must be done through anamnesis, physical examination, and advanced examination. Limited faciliiesy and lack of parental knowledge make the patients come late to health facility. The conclusion of this study is knowledge among parents and skills of health workers concerning congenital anomaly especially undescensus testis should be improved.

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“…7 Keberhasilan terapi HCG di RSCM yang dilaporkan pada tahun 2003 adalah 75% pada UDT yang teraba dan 50% pada yang tidak teraba. 8 Sampai saat ini, di Indonesia masih merekomendasikan pemberian terapi hormonal pada bayi usia kurang dari 1 tahun. 9 Hal tersebut senada dengan rekomendasi dari American Academy of Pediatrics (AAP) yang menyebutkan hormonal terapi masih memiliki dampak terhadap penurunan testis tergantung pada usia pasien saat dilakukan terapi.…”

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Dampak Jangka Panjang Terapi Hormonal Dibandingkan Pembedahan pada Undesensus Testis

Kresnawati

Pulungan

Tridjaja

2016

Self Cite

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Latar belakang. Pemberian terapi hormonal pada undesensus testis (UDT) masih direkomendasikan di Indonesia sedangkanConsensus Report of Nordic Countries menyatakan bahwa terapi lini pertama untuk undesensus testis adalah operasi dan terapihormonal tidak direkomendasikan lagi.Tujuan. Mengevaluasi dampak samping terapi hormonal dan pembedahan pada undesensus testis berdasarkan bukti ilmiah.Metode. Penelusuran pustaka database elektronik : Pubmed, Cochrane, Medline, Pediatrics.Hasil. Terdapat 11 penelitian mengenai dampak terapi pada UDT. Lima penelitian prospektif melakukan pemantauan sampaiusia pasien 3 tahun sedangkan 6 penelitian lainnya merupakan studi potong lintang pada pria dewasa dengan riwayat undesensustestis. Volume testis dan kualitas sperma lebih rendah pada pasien yang memiliki riwayat terapi hormonal dibandingkan denganpasien yang menjalani pembedahan saja. Risiko infertilitas meningkat (OR 4,7) pada pasien yang menjalani terapi hormonal.Risiko keganasan meningkat jika pembedahan dilakukan lebih dari usia 10 tahun.Kesimpulan. Terapi hormonal pada UDT dapat meningkatkan risiko infertilitas di kemudian hari oleh karena itu terapi hormonalsebaiknya tidak dianjurkan. Pasien dengan UDT berisiko menderita keganasan testis di usia dewasa dan orkiopleksi dini (sebelumusia 12 bulan) terbukti menurunkan risiko tersebut.

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Gambaran Klinis Kriptorkismus di Poliklinik Endokrinologi Anak RS Dr. Cipto Mangunkusumo, Jakarta, Tahun 1998 - 2002

Cited by 3 publications

References 3 publications

Efficacy of Vitamin-D Supplement on Thyroid Profile in Children with Graves’ Disease

Efficacy of Vitamin-D Supplement on Thyroid Profile in Children with Graves’ Disease

Perineal Ectopic Testis in One and A Half Year Old Child As A Rare Congenital Anomaly: A Case Report

Dampak Jangka Panjang Terapi Hormonal Dibandingkan Pembedahan pada Undesensus Testis

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