Further studies on the hematopoietic damage produced by a single dose of T-2 toxin in mice

Selenium Improves Bone Microenvironment-Related Hematopoiesis and Immunity in T-2 Toxin-Exposed Mice

“…The T-2 toxin is one of the most common mycotoxins in agriculture and the environment. Excessive exposure to the T-2 toxin damages the immune, hematopoietic, reproductive, and nervous systems, posing a great threat to human health and the breeding industry. According to European Food Safety Authority investigations, most animals experience adverse effects at the dose of 0.1–2 mg/kg BW T-2 toxin exposure .…”

Selenium Improves Bone Microenvironment-Related Hematopoiesis and Immunity in T-2 Toxin-Exposed Mice

“…The T-2 toxin is one of the most common mycotoxins in agriculture and the environment. Excessive exposure to the T-2 toxin damages the immune, hematopoietic, reproductive, and nervous systems, posing a great threat to human health and the breeding industry. According to European Food Safety Authority investigations, most animals experience adverse effects at the dose of 0.1–2 mg/kg BW T-2 toxin exposure .…”

Biochemistry and metabolism of mycotoxins: A review

“…The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992). In another study , DON inhibited granulo-monocytic progenitors.…”

“…In another in vitro study where murine peritoneal macrophages were used (Ayral et al, 1992), DON and DAS were shown to inhibit the phagocytic activity, microbicidal activity, and superoxide anion production. The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992).…”

Efectos de la intoxicación aguda por micotoxina T-2 en el ratón

“…También fue evidente la necrosis de las células de las placas de Peyer intestinales (72). En médula ósea, animales tratados con micotoxina T-2 evidenciaron una reducción en el número de las células precursoras de las seríes granulocítica y megacariocítica (43) y una inhibición en la capacidad clonogénica de las células progenitoras de las líneas granulocítica-monocítica (26). Por otro lado, se han descripto lesiones en el tracto gastrointestinal de ratones inoculados con micotoxina T-2.…”

Selenium Improves Bone Microenvironment-Related Hematopoiesis and Immunity in T-2 Toxin-Exposed Mice

“…The T-2 toxin is one of the most common mycotoxins in agriculture and the environment. Excessive exposure to the T-2 toxin damages the immune, hematopoietic, reproductive, and nervous systems, posing a great threat to human health and the breeding industry. According to European Food Safety Authority investigations, most animals experience adverse effects at the dose of 0.1–2 mg/kg BW T-2 toxin exposure .…”

Biochemistry and metabolism of mycotoxins: A review

“…The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992). In another study , DON inhibited granulo-monocytic progenitors.…”

“…In another in vitro study where murine peritoneal macrophages were used (Ayral et al, 1992), DON and DAS were shown to inhibit the phagocytic activity, microbicidal activity, and superoxide anion production. The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992).…”

Efectos de la intoxicación aguda por micotoxina T-2 en el ratón

“…También fue evidente la necrosis de las células de las placas de Peyer intestinales (72). En médula ósea, animales tratados con micotoxina T-2 evidenciaron una reducción en el número de las células precursoras de las seríes granulocítica y megacariocítica (43) y una inhibición en la capacidad clonogénica de las células progenitoras de las líneas granulocítica-monocítica (26). Por otro lado, se han descripto lesiones en el tracto gastrointestinal de ratones inoculados con micotoxina T-2.…”

Selenium Improves Bone Microenvironment-Related Hematopoiesis and Immunity in T-2 Toxin-Exposed Mice

“…The T-2 toxin is one of the most common mycotoxins in agriculture and the environment. Excessive exposure to the T-2 toxin damages the immune, hematopoietic, reproductive, and nervous systems, posing a great threat to human health and the breeding industry. According to European Food Safety Authority investigations, most animals experience adverse effects at the dose of 0.1–2 mg/kg BW T-2 toxin exposure .…”

Biochemistry and metabolism of mycotoxins: A review

“…The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992). In another study , DON inhibited granulo-monocytic progenitors.…”

“…In another in vitro study where murine peritoneal macrophages were used (Ayral et al, 1992), DON and DAS were shown to inhibit the phagocytic activity, microbicidal activity, and superoxide anion production. The actions of trichothecenes at the hematological level have been illustrated in several studies (Faifer et al, 1992;Lautraite et al, 1997;. For example, T-2 toxin reduced granulocyte macrophage colony-forming cells in the bone marrow of mice (Faifer et al, 1992).…”

Efectos de la intoxicación aguda por micotoxina T-2 en el ratón

“…También fue evidente la necrosis de las células de las placas de Peyer intestinales (72). En médula ósea, animales tratados con micotoxina T-2 evidenciaron una reducción en el número de las células precursoras de las seríes granulocítica y megacariocítica (43) y una inhibición en la capacidad clonogénica de las células progenitoras de las líneas granulocítica-monocítica (26). Por otro lado, se han descripto lesiones en el tracto gastrointestinal de ratones inoculados con micotoxina T-2.…”