Furosemide Ototoxicity Is Enhanced in Analbuminemic Rats

Rybak, Leonard P.; Whitworth, Craig; Scott, Virgil

doi:10.1001/archotol.1993.01880190054011

Archives of Otolaryngology - Head and Neck Surgery

1993

DOI: 10.1001/archotol.1993.01880190054011

|Get access via publisher |Summarize |Cite

|

Sign up to set email alerts

Furosemide Ototoxicity Is Enhanced in Analbuminemic Rats

Leonard P. Rybak

¹

,

Craig Whitworth²,

Virgil Scott³

Help me understand this report

Cited by 14 publications

(1 citation statement)

References 25 publications

Supporting

0

Mentioning

1

Contrasting

0

Unclassified

0

Order By: Relevance

“…It follows that a patient in hepatic and renal failure would be susceptible to higher concentrations of drug and therefore an increased risk of ototoxicity. Specifically, Rybak et al have shown an increased reduction in the endocochlear potential in a low serum albumin mouse model of furosemide ototoxicity . Prior to death the albumin level in case 1 was abnormally low and liver function tests abnormally high consistent with hepatic failure.…”

Section: Discussionmentioning

confidence: 99%

Temporal bone histopathology of furosemide ototoxicity

Santos

¹

,

Nadol

²

2017

Laryngoscope Investig Oto

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…It follows that a patient in hepatic and renal failure would be susceptible to higher concentrations of drug and therefore an increased risk of ototoxicity. Specifically, Rybak et al have shown an increased reduction in the endocochlear potential in a low serum albumin mouse model of furosemide ototoxicity . Prior to death the albumin level in case 1 was abnormally low and liver function tests abnormally high consistent with hepatic failure.…”

Section: Discussionmentioning

confidence: 99%

Temporal bone histopathology of furosemide ototoxicity

Santos

¹

,

Nadol

²

2017

Laryngoscope Investig Oto

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

Use of Otoacoustic Emissions to Screen for Hearing Loss in Critically III Patients

Hamill-Ruth

¹

,

Ruth

²

,

Googer

³

et al. 1998

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

Dose-response relationships for furosemide ototoxicity in rat

Whitworth¹,

Morris

²

,

Scott

³

et al. 1993

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

Scite is an AI-powered platform that helps researchers discover and evaluate scientific literature through Smart Citations, showing whether studies support or contradict a claim. Now part of Research Solutions, Scite has indexed 1.6B+ citations, partners with 30+ publishers, and serves 2M users worldwide.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA