2017
DOI: 10.1590/1519-6984.03716
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Abstract: Garlic (Allium sativum L.) is grown all over the world as seasoning and medicinal vegetable since 3,000 BC. Allicin is the main component of garlic, being attributed to it the most of its biological activities, such as bactericidal, antifungal and antiviral actions. However, other compounds of garlic present antioxidant, hypocholesterolemic, vasodilator activities, protective action against different types of cancer, and immunomodulatory. Fungal infections are important causes of morbidity and mortality in peo… Show more

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Cited by 17 publications
(17 citation statements)
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References 16 publications
(17 reference statements)
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“…A. sativum is reported to have numerous biological properties, such as antibacterial, antifungal, anti-carcinogenic, antioxidant, anti-diabetic, reno-protective, anti-atherosclerotic, and anti-hypertensive effects. Cloves of this traditional medicinal plant contain several potent components, such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids [ 108 , 109 , 254 , 255 , 256 ], due to which it is mostly used for treatment of various disorders [ 106 , 107 , 108 , 109 , 257 ]. On the other hand, an in vitro study conducted by Ziai et al, 2009 on A. sativum and its potential efficacy to inhibit the ACE-2 receptor reported some effective results [ 94 ].…”
Section: Known Medicinal Plants Acting On Ace-2 Receptormentioning
confidence: 99%
“…A. sativum is reported to have numerous biological properties, such as antibacterial, antifungal, anti-carcinogenic, antioxidant, anti-diabetic, reno-protective, anti-atherosclerotic, and anti-hypertensive effects. Cloves of this traditional medicinal plant contain several potent components, such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids [ 108 , 109 , 254 , 255 , 256 ], due to which it is mostly used for treatment of various disorders [ 106 , 107 , 108 , 109 , 257 ]. On the other hand, an in vitro study conducted by Ziai et al, 2009 on A. sativum and its potential efficacy to inhibit the ACE-2 receptor reported some effective results [ 94 ].…”
Section: Known Medicinal Plants Acting On Ace-2 Receptormentioning
confidence: 99%
“…Regular consumption increases the level of pro-inflammatory cytokines such as IL-1β, IL-12 in infected Swiss mice, and anti-inflammatory cytokine IL-10 in healthy animals. Excessive inflammation may be a natural approach to treating fungal infection [188].…”
Section: Fungal Skin Diseasementioning
confidence: 99%
“…It has been confirmed that garlic extract has an antibacterial effect on human dental plaque microbiota [15,16]. Meanwhile, the strong inhibitory effect of garlic extract was also confirmed on dimorphic fungi such as Sporothrix schenckii [17]. Therefore, it is possible that garlic extract can exert its inhibitory effect on pathogens that cause rot disease in pomegranate.…”
Section: Introductionmentioning
confidence: 94%