2019
DOI: 10.3389/fnhum.2019.00350
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Abstract: For the management of Parkinson’s disease (PD), the concept of forced exercise (FE) has drawn interest. In PD subjects, the FE executed with lower limbs has been shown to lessen symptoms and to promote brain adaptive changes. Our study is aimed to investigate the effect of an upper-limb exercise, conceptually comparable with the FE, in PD. Upper-limb exercise was achieved in a sitting position by using a specially designed device (Angel’s Wings®). Clinical data, computerized dynamic posturography, magnetic res… Show more

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Cited by 10 publications
(8 citation statements)
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“…A total of 2,874 publications were selected through databases for initial screening, and among them, 1,201 duplicates were removed, and 1,651 articles were excluded as they did not satisfy the inclusion criteria. As a result, through the full text of 22 screened studies, only seven fully satisfied all the criteria for inclusion in the meta-analysis ( Shine et al, 2013 ; Duchesne et al, 2016 ; Agosta et al, 2017 ; Kelly et al, 2017 ; Messa et al, 2019 ; Segura et al, 2020 ; Silva-Batista et al, 2020 ). A flowchart of this process is shown in Figure 1 .…”
Section: Resultsmentioning
confidence: 99%
“…A total of 2,874 publications were selected through databases for initial screening, and among them, 1,201 duplicates were removed, and 1,651 articles were excluded as they did not satisfy the inclusion criteria. As a result, through the full text of 22 screened studies, only seven fully satisfied all the criteria for inclusion in the meta-analysis ( Shine et al, 2013 ; Duchesne et al, 2016 ; Agosta et al, 2017 ; Kelly et al, 2017 ; Messa et al, 2019 ; Segura et al, 2020 ; Silva-Batista et al, 2020 ). A flowchart of this process is shown in Figure 1 .…”
Section: Resultsmentioning
confidence: 99%
“…37 As the final cortical output of motor commands, the MI send signals from premotor cerebral cortical sites to the spinal cord. 38 According to previous studies, LPE was presumed to be mediated by a more complicated interaction of the endocrine, peripheral nervous and central nervous systems. 39,40 The lack of structural associations in our study might suggest weaker information communication and inhibitory control.…”
Section: Discussionmentioning
confidence: 99%
“…The MI plays a central role in motor‐related information processing 37 . As the final cortical output of motor commands, the MI send signals from premotor cerebral cortical sites to the spinal cord 38 . According to previous studies, LPE was presumed to be mediated by a more complicated interaction of the endocrine, peripheral nervous and central nervous systems 39,40 .…”
Section: Discussionmentioning
confidence: 99%
“…A study published in 2019 looked at the changes in areas of activation on functional MRI in PD patients when exercise was targeted to the upper limbs. 33 Studies such as this are important for determining the efficacy of upper limb exercises on changes in neural functioning given that many patients lack the balance and mobility to perform exercises reliant on the lower limbs. Upper-limb exercises were performed in a seated position using a specially designed device known as Angel’s Wings©.…”
Section: Methodsmentioning
confidence: 99%
“…Overall, the results of the study indicate that an exercise routine focused on the upper limbs leads to increased activity in the central nervous system similar to that seen in lower limb targeted therapies and is an acceptable alternative for patients seeking functional improvement. 33…”
Section: Methodsmentioning
confidence: 99%