2021
DOI: 10.1111/jocs.15452
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Abstract: Background and Aim of the Study The frozen elephant trunk (FET) procedure became a popular entity for utilization in aortic arch aneurysm disease. However, its proper mortality and morbidities as well as the predictors of outcomes are poorly identified. This systematic review and meta‐analysis explore FET outcomes and its predictors with a focus on zone aortic proximalization. Methods We searched PubMed/MEDLINE, EMBASE, and Scopus databases from their beginning to June 2020 to find studies reporting the outcom… Show more

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Cited by 21 publications
(33 citation statements)
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“…It is well established that each pathology is associated with specific risk profiles, affecting short-and long-term outcomes after aortic arch repair. 46 In addition to the type of aorta pathology, cannulation site, concomitant surgery, neurological monitoring, the method surgeon approached to the left subclavian artery, and intra-operative measures would change the course of postoperative outcomes. So, we herein conducted a systematic review focused on the outcome of FET deployment in ATAAD patients who needs total arch replacement, taking into account peri-operative features.…”
Section: Discussionmentioning
confidence: 99%
“…It is well established that each pathology is associated with specific risk profiles, affecting short-and long-term outcomes after aortic arch repair. 46 In addition to the type of aorta pathology, cannulation site, concomitant surgery, neurological monitoring, the method surgeon approached to the left subclavian artery, and intra-operative measures would change the course of postoperative outcomes. So, we herein conducted a systematic review focused on the outcome of FET deployment in ATAAD patients who needs total arch replacement, taking into account peri-operative features.…”
Section: Discussionmentioning
confidence: 99%
“…The FET procedure is a promising and an evolving technique that is associated with acceptable rates of mortality and morbidity compared to the conventional elephant trunk procedure in the management of complex thoracic aortic pathologies. 51 The development of coagulopathy (i.e., reoperation for bleeding and blood products transfusion) in aortic surgery is commonly observed in patients undergoing repair of aneurysm or dissection. 52,53 According to a position paper reported by the Vascular Domain of EACTS, postoperative re-exploration because of bleeding ranged between 2.5-30%.…”
Section: Discussionmentioning
confidence: 99%
“…Apart from graft sizing, several FET devices are available, [67][68][69][70][71] and their usage in clinical practice is evolving so that studies for outcomes of such devices are being increased in literature. 51 The globally used tetrafurcate Thoraflex Hybrid ® stent-graft provides separate reimplantation of supra-aortic vessels, an easier anastomosis to the distal aortic arch, and radio-opaque markers in the stented part.…”
Section: Discussionmentioning
confidence: 99%
“…Having evaluated the difference in surgical approach between Z‐2‐FET and Z‐0‐FET, the comparative efficacies of both procedures should be analyzed in terms of postoperative outcome. The improved clinical outcomes associated with proximalization from Z‐3‐FET to Z‐2‐FET have been widely documented, and indeed this has spurred a general shift in preference towards Z‐2‐FET over the last few years 1,5,24 . Z‐2‐FET has been demonstrated to yield fewer long‐term adverse events, such as mortality, spinal cord injury, visceral ischemia, re‐intervention, and renal complications, than Z‐3‐FET 1,5 .…”
Section: Zone 2 Versus Zone 0: Clinical Outcomesmentioning
confidence: 99%
“…Spinal cord ischemia (SCI) can occur in up to 7.3% of cases, while cerebrovascular accidents occur in up to 15.9% of cases 5 . A meta‐analysis by Rezaei et al 1 reports a pooled estimate of incidence of 7% and 3.5% for CVA and paraplegia respectively. Intriguingly, Yamamoto et al 16 reported no cases of SCI or CVA following Z‐0‐FET, while the single mortality in Jakob et als' 17 report was attributed to cerebrovascular insufficiency.…”
Section: Zone 2 Versus Zone 0: Clinical Outcomesmentioning
confidence: 99%