Epilepsy in Children - Clinical and Social Aspects 2011
DOI: 10.5772/18443
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Cited by 5 publications
(5 citation statements)
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References 115 publications
(173 reference statements)
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“…and adolescents with epileptic abnormalities involving the frontal lobe show significant impairment of executive abilities (abilities primarily processed by the frontal lobe), which can relate to intellectual impairments [7]. EEG monitoring can detect subclinical paroxysmal abnormalities, which may affect attention and other aspects of cognitive functioning in various ways, even in the absence of clinical seizures.…”
Section: Childrenmentioning
confidence: 99%
“…and adolescents with epileptic abnormalities involving the frontal lobe show significant impairment of executive abilities (abilities primarily processed by the frontal lobe), which can relate to intellectual impairments [7]. EEG monitoring can detect subclinical paroxysmal abnormalities, which may affect attention and other aspects of cognitive functioning in various ways, even in the absence of clinical seizures.…”
Section: Childrenmentioning
confidence: 99%
“…Given the impact of behavioral disturbances and their seemingly high prevalence, there is a need for studies of the etiology of seizureassociated behavioral disturbances. Frontal localization of an epileptic focus correlates with executive dysfunction [39]. Several hypotheses have been presented: (a) the high prevalence of similar psychiatric changes among patients with primary frontal and primary temporal epileptogenic zones has been related to the intimate connection of the frontal and temporal limbic system [40]; (b) cognitive and behavioral problems can be the result of epilepsy-related factors, including the age of onset of seizures, the number of seizures, the occurrence of secondary generalized seizures, and the location and extension of the epileptic focus [41]; (c) the association between psychosis or ictal fear and frontal lobe epilepsy has been related to the reciprocal connections between the amygdala, orbitofrontal, and anterior cingulate regions and between the frontal and temporal lobes through the uncinate fasciculus and the superior longitudinal fasciculus [42]; (d) aggressive behavior has been related to activation of limbic activity [38]; and (e) spreading of discharges from primary foci to other frontal, temporal, or limbic structures may be another explanation [43].…”
Section: Pathological Mechanisms Underlying Cognitive and Behavioral mentioning
confidence: 99%
“…These results may support the proposal by Austin et al that seizure recurrence may be a predictor of behavior issues. However, it is important first to consider that the majority of studies contain speculations on the qualitative analysis of the data without supporting statistical analyses [35]. Further research will be needed to address these limitations.…”
Section: The Relationship Between Cognitive/behavioral Impairments An...mentioning
confidence: 99%