From stem cells to human development: a distinctly human perspective on early embryology, cellular differentiation and translational research

Abstract

Over 100 scientists with common interests in human development, disease and regeneration gathered in late September 2016 for The Company of Biologists' second 'From Stem Cells to Human Development' meeting held in historic Southbridge. In this Meeting Review, we highlight some of the exciting new findings that were presented, and discuss emerging themes and convergences in human development and disease that arose during these discussions.

Transplantation of Bone Marrow Cells Preactivated With Sodium Nitroprusside Improves Acute Wound Healing in Rabbits

“…So the BMCs research tells about the proper sequence of growth factor, that is, needed for specific tissue regeneration. 45 The NO donor helps in accelerating the healing process with BMCs, so it was required to enhance their potential to differentiate the cells that enabled them in migration and the regeneration of the affected area. In this study pretreated BMCs with NaNP enhanced the therapeutic potential of BM-derived cells which were obtained from healthy rabbits and induced wound to create injury; these cells showed tremendous ability to proliferate in that area.…”

The times they are a-changin’

“…Finally, in 2014 and 2016, we organized very successful dedicated meetings on the theme 'From Stem Cells to Human Development'. The 2016 meeting showcased the newest developments in the field of human developmental biology, including progress in emerging technologies such as organoids, bioengineering and single cell analyses (Craft and Johnson, 2017). We hope to continue this series of meetings in 2018, so look out for further announcements.…”