Autism spectrum disorders (ASD) are characterized by difficulties of socialization, disorders of verbal communication, restricted and stereotyped patterns of behaviors. Firstly, the paper reports tools of the user-centered design (UCD) used as well participants involved in the design of interactive collaborative system for children with ASD. Then, we describe the UCD deployed to design a vocal communication tool (VCT) between an adult with ASD and his family caregivers. The analyses of interviews demonstrate a strong need for a collaborative assistive technology based on voice interaction to avoid the family caregivers repeating the same sentences to the adult with ASD and, to create a friendly atmosphere at home. Observations in a real life environment demonstrate that the VCT is useful and accepted by the adult with ASD and his family. The work is not complete and issues such as designing a spoken dialogue system in the smart home need further works. The study of the type of voice synthesis (human or text-to-speech synthesis) is also an open question.